Nuuk

Sedentary behavior among medical inpatients is linked to hospital-associated functional decline, threatening patients functional ability and independence. This multicenter study aims to assess the impact of a digital intervention designed to reduce sedentary time and increase physical activity among medical inpatients. The trial will include 400 patients from multiple hospitals across Copenhagen, Aalborg, Trshavn, and Nuuk and focuses on evaluating physical activity through digital feedback and nudging. Participants will be randomly assigned in a stepped-wedge cluster design to either standard care with measurement of physical activity using accelerometers or to an intervention group receiving digital feedback and nudging aimed at patients and healthcare staff. This feedback is based on the patients physical activity levels and seeks to encourage more movement during their hospital stay. The intervention period will last up to 7 days for each participant. During the study, participants physical activity will be continuously monitored using accelerometers to measure daily average activity time. Data will be collected from the time of enrollment until the end of their participation, not exceeding 7 days. Researchers will track adherence to the intervention and measure the primary outcome of daily average physical activity minutes. Safety and medical suitability for participation will be reviewed by medical staff prior to inclusion.

Researchers are studying the phenotypic and genotypic characteristics of people living with type 2 diabetes and severe obesity in Greenland, focusing on how genetic factors influence disease development and complications. The study also explores the prevalence of obstructive sleep apnea OSA in this population and aims to develop personalized medicine approaches based on genotype, especially concerning MODY diabetes and metabolic disorders. Participants will undergo whole genome sequencing to identify genetic variants linked to diabetes and insulin resistance. They will be examined for diabetic complications and sleep apnea using devices like the VAGUS handheld device for cardiovascular autonomic neuropathy and the NightOwl device for sleep apnea monitoring over three nights. Those diagnosed with severe sleep apnea may receive continuous positive airway pressure CPAP treatment. During the study, participants will complete questionnaires on quality of life and daytime sleepiness and undergo clinical measurements of body size and airway features. Blood samples will be collected for genetic testing. The research team will track diabetic complications, sleep apnea presence, and CPAP treatment compliance and effects over six months. The study provides detailed health assessments without randomizing treatment but offers appropriate care when criteria are met.