Basse Terre

Researchers are investigating how the blood levels of the S100B protein vary among healthy individuals from different ethnic backgrounds in Guadeloupe. S100B is a protein used to help manage minor to moderate traumatic brain injuries by potentially reducing the number of CT scans needed. Previous studies suggest that people with a Black skin phenotype may naturally have higher levels of S100B compared to those with Asian or Caucasian phenotypes, which could affect the accuracy of current testing thresholds, especially in populations like Guadeloupe where many people have a Black phenotype. The study will involve hospital staff from the University Hospital of Guadeloupe and the Hospital of Basse-Terre who meet specific eligibility criteria. After providing informed consent and completing a questionnaire about their ethnicity, age, sex, and weight, participants will have a blood sample taken. This sample will be analyzed at the University Hospital's biochemistry laboratory to measure their S100B protein levels. Participants will be involved in a one-time visit where they complete the questionnaire and provide a blood sample. The study aims to assess the natural variability of S100B levels according to skin phenotype and ethnicity. This includes comparing baseline S100B levels among different groups. Safety monitoring and long-term follow-up are not part of this study, which focuses on healthy subjects within an age range of 18 to 65 years.