Lodi

This research aims to develop a system for continuously evaluating healthcare quality in semi-intensive care units. By collecting patient data and hospital structure information, the study will identify indicators of unsuccessful care tailored to different patient types. These indicators will help assess the overall quality of care in each semi-intensive care unit over time. The study will last for five years, from 2021 to 2025, during which data from patients admitted to semi-intensive care units will be gathered. Annually, a detailed report will be produced to analyze and compare the results from each unit, helping to track improvements or identify areas needing attention. Participants include all patients hospitalized in participating semi-intensive care units, with an expected total of at least 39,000 patients over the study period. Researchers will monitor outcomes for various patient risk groups to assess healthcare quality. The study involves ongoing data collection and yearly evaluations to support continuous quality improvement in these care units.

This research aims to evaluate the usefulness of bronchoscopy in patients who have haemoptysis, which is coughing up blood from the airways, but whose chest CT scans show no clear or diagnostic results. The study focuses on understanding how bronchoscopy can help identify the cause of bleeding, detect hidden cancers, and explore clinical features in these patients. It is a prospective, observational, multicenter study involving multiple respiratory units across Europe. Participants with haemoptysis and negative or non-diagnostic chest CT scans will undergo bronchoscopy within two weeks following the CT scan. During bronchoscopy, various procedures such as biopsies, washings, and needle aspirations may be performed to obtain diagnostic samples. The study will include adults aged 18 years and older, with chest CT scans done within 72 hours of the last haemoptysis episode. Bronchoscopy is performed to try to find the source of bleeding or any hidden lung cancers not seen on CT. Participants will have a pulmonary exam and blood tests before bronchoscopy and will be followed for 12 months with telephone interviews at one, three, six, and twelve months. If haemoptysis recurs, clinical evaluation may be done. Researchers will measure the proportion of patients diagnosed through bronchoscopy, the detection of occult malignancies, changes in treatment due to bronchoscopy findings, recurrence of symptoms, and mortality over one year. Safety and clinical outcomes will be monitored throughout the follow-up period.