Ar Ramtha

Researchers are evaluating the effects of progressive resistance exercises and aerobic exercises on cartilage structure and physical function in adults aged 35 to 55 with degenerative meniscus tears. This randomized controlled trial aims to understand how these exercise programs impact cartilage health before knee osteoarthritis develops. The study also seeks to assess clinical outcomes like pain and disability, while testing the feasibility of recruiting and keeping participants for a larger future trial. Participants will be randomly assigned to one of three groups for a 3-month supervised program: progressive resistance exercise focused on strengthening the quadriceps using the Daily Adjustable Progressive Resistance Exercise technique; aerobic exercise using a stationary bike to improve cardiovascular fitness and knee mobility; or a control group receiving standard care with general strength and balance exercises. MRI T2 mapping will be used at the start and after 3 months to observe changes in cartilage composition. Throughout the study, participants will complete patient-reported questionnaires such as the Knee Injury and Osteoarthritis Outcome Score and the International Knee Documentation Committee score. Physical function will be assessed with tests like the single-leg squat, single-leg hop, sit-to-stand on one foot, step-up, and treadmill exercise. Researchers will monitor changes in cartilage through MRI and track clinical improvements and adherence to the exercise program, with follow-ups at baseline, 3 months, 24 months, and 5 years.