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Healthy Volunteer
Insomnia is a common sleep disorder affecting a wide range of people including athletes, older adults, university students, and those with metabolic syndrome. It is linked to health problems like metabolic dysfunction, cardiovascular disease, and DNA damage due to factors such as hormonal imbalances, oxidative stress, and energy metabolism changes. This study aims to explore how insomnia impacts body composition, heart and lung fitness, metabolic flexibility, and DNA stability across these groups, while identifying biological and lifestyle factors that contribute to insomnia and its health effects. Participants will undergo several tests including a cardiopulmonary exercise test to measure oxygen uptake and metabolic flexibility, bioelectrical impedance to assess body composition, and a micronucleus assay to examine DNA damage from oral cells. They will also complete questionnaires on physical activity, sleep quality, stress, depression, and substance use. Blood samples will be collected to analyze glucose, lipids, insulin, hormones, and genetic factors related to sleep disorders. Half of the subjects will wear devices to track physical activity and sleep quality. Throughout the study, researchers will evaluate insomnia severity, daytime sleepiness, and sleep quality using validated scales and wearable technology. They will also assess fitness, metabolic health, and DNA integrity through physical tests and laboratory analyses. The study seeks to understand how insomnia influences these health measures and to provide insights for developing targeted prevention and treatment strategies. Participant involvement includes one main assessment day with multiple evaluations and no long-term follow-up required.