Rabat

Researchers are collecting detailed information about patients with venous thromboembolism (VTE), which includes blood clots in veins such as deep-vein thrombosis and pulmonary embolism. The project aims to improve doctors' understanding of VTE, especially in patients often excluded from clinical trials, like pregnant women, elderly individuals, cancer patients, and those with other complex health issues. The goal is to reduce deaths, clot recurrence, bleeding problems, and artery-related events by sharing this knowledge widely. The study involves gathering extensive data on each patient's health status, treatments, and outcomes during the first three months of therapy. This registry is available online to help doctors quickly find information on patients with similar medical profiles and make informed decisions about managing high-risk individuals. There are no specific interventions being tested; instead, the focus is on collecting real-world patient data. Participants provide informed consent and are followed for at least three years to monitor for new clot events and complications. Researchers track recurrences of VTE, bleeding episodes, and deaths, aiming to create tools that predict which patients are most at risk for problems. This ongoing data collection supports improving care and guiding treatment decisions for diverse patient groups over time.

Researchers are evaluating the effectiveness of robotic training compared to conventional physiotherapy rehabilitation in patients with adhesive capsulitis of the shoulder, a condition characterized by pain and limited shoulder movement. The study highlights the emerging role of robotics and virtual reality technologies in enhancing functional rehabilitation and promoting brain reorganization to improve patient autonomy. Participants will receive either robotic training involving continuous passive mobilization using the Armeo Spring device or conventional rehabilitation sessions guided by a physiotherapist. These treatments aim to improve shoulder function and reduce disability, with the study tracking progress over time. Throughout the study, participants' shoulder function will be assessed at multiple time points—3 weeks, 6 weeks, 3 months, 6 months, 9 months, and 12 months—using the Shoulder Pain and Disability Index (SPADI). Researchers will monitor changes in pain and movement limitation to compare the benefits of each rehabilitation method.

Researchers are evaluating the quality of primary healthcare systems for patients with arterial hypertension (HTA) in Morocco, focusing on its high prevalence and impact on illness and death rates. The study aims to understand different types of hypertension, related complications, and how blood pressure is managed across the country. It also seeks to compare current practices with past data and European clinical guidelines to improve prevention and treatment strategies. This observational study uses an electronic registry to collect anonymous medical data from primary care and hospital settings. Trained investigators will standardize blood pressure measurements to ensure accuracy. Data collected will include patient height, weight, waist size, blood pressure readings using validated devices, and metabolic tests like blood glucose and cholesterol levels. Information about cardiovascular complications will also be recorded. The study follows a cohort design with a cross-sectional view and plans to track patients for one year. Participants will provide informed consent to include their information in the registry. Researchers will analyze prevalence, hypertension types, and geographic distribution within Morocco. They will also compare findings with previous years and other North African countries. The study monitors blood pressure control, treatment patterns, complications, and metabolic health. These results aim to identify gaps and improvements in primary care for hypertension, helping to enhance patient management and outcomes over the 2024-2026 period.

Researchers are evaluating whether combining lumbopelvic postural rehabilitation with pelvic floor muscle training (PFMT) is more effective than PFMT alone in women with urinary incontinence. The study focuses on assessing improvements in urinary incontinence severity, urinary symptoms, pelvic floor muscle strength, patient-reported overall improvement, and quality of life. This clinical trial includes women diagnosed with stress, urge, or mixed urinary incontinence as per International Continence Society terminology. Participants will be randomly assigned to one of two groups for a 12-week treatment period. The experimental group will receive pelvic floor muscle training three times per week alongside two weekly sessions of lumbopelvic postural rehabilitation using posturography, which involves seated exercises targeting stability and mobility of the lumbopelvic region. The control group will perform pelvic floor muscle training alone three times per week, including one supervised hospital session and three home sessions weekly, with exercises performed in supine and seated positions. Participants will be assessed at the start of the study, at 6 weeks, and at 12 weeks. Researchers will use questionnaires like the International Consultation on Incontinence Questionnaire - Urinary Incontinence Short Form to measure urinary incontinence severity. Other assessments include urinary symptom profiles and pelvic floor muscle strength evaluations. Monitoring will also cover patient-reported improvements and quality of life during the study period.

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, with increasing prevalence in Morocco. Between 2010 and 2012, the "All with heart" Association conducted a large cardiovascular screening involving over 10,000 adults aged 40 and older in the Greater Casablanca region. This study aims to follow up on these participants 10 years later to evaluate long-term cardiovascular outcomes and to develop a risk score specific to the Moroccan population. The study involves contacting participants or their families through phone calls, WhatsApp, or SMS to collect follow-up data on cardiovascular deaths, heart attacks, and strokes. Statistical methods such as survival analysis and multivariate logistic regression will be used to identify key risk factors and to create a predictive model tailored for Morocco. Participants or their families provide written informed consent before data collection. During the study, researchers will gather information on major cardiovascular events over the 10-year period since initial screening. The main outcomes include the incidence of these events and the validation of the Morocco-specific cardiovascular risk score. The study has ethical approval from the Rabat Ethics Committee and aims to improve understanding of cardiovascular risk evolution and support prevention and management strategies in Morocco.