Tondela

Spontaneous coronary artery dissection (SCAD) is a cause of acute coronary syndromes that mainly affects young women without typical risk factors for atherosclerosis. Recent advances in understanding SCAD have come from regional and national registries, but there is a need for international collaboration to better understand diagnosis, treatment, and outcomes. This study aims to create the first pan-European SCAD registry to improve knowledge, guide clinical practice, and support research. This is an observational, multicenter, international retrospective and prospective cohort study involving at least 500 patients recruited prospectively and 500 historical cases. Data will be collected from patients diagnosed with SCAD within the past 10 years, including information from the first SCAD event and yearly follow-ups up to 5 years after enrollment. Approximately 30 countries and 120 sites will participate, and no treatments or interventions will be given as part of the study. Participants will have their medical records and coronary angiographic images reviewed at baseline and will be followed annually for up to 5 years. Information collected will include patient status, vital signs, recurrent SCAD events, imaging results, medications, menstrual and obstetric history, and discharge details. The study aims to gather comprehensive data to better understand SCAD management and long-term outcomes.