Cerdanyola Del Valles

Researchers are evaluating an AI-based narrative intervention called Aurora, designed to support emotional expression, identity processes, and emotional well-being in both clinical and non-clinical populations. The study includes healthy adults, adults with diagnosed mental disorders in residential care, and healthy older adults. Aurora uses a chatbot-mediated storytelling process guided by licensed mental health professionals to help participants create a personalized life narrative or life book. The study aims to assess emotional affect, mental well-being, and recovery outcomes through quantitative and qualitative measures. Aurora is delivered in structured guided sessions supervised by trained facilitators. There are three study arms a single-session arm for healthy adults to assess usability and emotional safety a four-session intervention over two weeks for adults with mental disorders in residential care and a two-session intervention over two weeks for healthy older adults aged 65 and above. Sessions involve narrative reconstruction with written content and optional audio contributions. The interventions are conducted in secure professional environments with data protection compliance. Participants provide informed consent and engage in guided storytelling sessions according to their assigned arm. Assessments include pre- and post-session affect measures, usability surveys, satisfaction ratings, and qualitative feedback. For adults with mental disorders and healthy older adults, ecological momentary assessment is conducted before, during, and after the intervention. The study carefully monitors emotional safety and anonymizes data. Participation duration varies by arm, ranging from a single session to multiple guided sessions over two weeks with follow-up assessments.

Researchers are studying sentinel lymph node detection in patients with breast cancer. The trial aims to compare the usual detection method using technetium 99 with a new tracer called indocyanine green to see how well each detects lymph nodes. This observational study is sponsored by the Omphis Foundation and includes patients who are candidates for sentinel lymph node detection. On the day of surgery, 1 ml of indocyanine green will be injected around the areola. After waiting 5 minutes, surgeons will detect and remove the lymph node using this tracer. The usual technique with technetium 99 will also be applied, and researchers will compare the number of lymph nodes detected by each method. Participants will undergo surgery where both tracers are used to find lymph nodes. Researchers will measure how many lymph nodes are found with each tracer, the number of positive lymph nodes, and the surgery duration in minutes. The study will include patients from January 2024 until January 2029, with ongoing monitoring of these outcomes throughout this period.