Vic

Researchers are evaluating the safety and effectiveness of UBT251, a medicine not yet available for prescription, in adults with type 2 diabetes. This study compares UBT251 with semaglutide, an already approved treatment, and their respective placebos. The goal is to see how well different doses of UBT251 lower blood sugar over time. Participants will be randomly assigned to receive either UBT251, UBT251 placebo, semaglutide, or semaglutide placebo. All treatments are given once weekly by injection under the skin. The study follows participants over several weeks, measuring effects at weeks 16, 28, and 40, focusing on blood sugar control and body weight changes. Throughout the study, participants will have regular assessments including blood tests to measure glycated hemoglobin HbA1c, insulin resistance, beta-cell function, fasting glucose, body measurements, blood pressure, cholesterol levels, and other health markers. Safety is monitored by tracking any adverse events, with total participation lasting up to 40 weeks of treatment plus additional safety follow-up.

The GEROS Project is designed to develop and implement a Service-Learning program that combines Comprehensive Geriatric Assessment CGA and health promotion for older adults aged 60 and above. It involves university students from various health-related fields and aims to foster intergenerational learning and community engagement. The study follows a non-experimental mixed-method design and focuses on evaluating frailty, intrinsic capacity, quality of life, and other health indicators in participating older adults. Participants will receive a series of three sessions at the University of Vic - Central University of Catalonia, where students supervised by health professionals conduct CGA evaluations. Following the assessment, users receive a report with their CGA results along with personalized health education and recommendations. The program integrates practical student training with real-world health promotion for older adults. During the study, researchers will assess frailty and quality of life at baseline, and measure satisfaction and self-perceived knowledge and skills of both students and older adult participants after the intervention sessions. Data will be collected through questionnaires and recorded using REDCap. The study supports active aging and aligns with global health and equality goals, with total participation spanning up to 2-4 weeks after intervention.

Researchers are investigating the relationship between motor skills and sensory processing in children aged 4 to 11 years who have either typical or atypical neurodevelopment, including Autism Spectrum Disorder ASD, Attention Deficit Hyperactivity Disorder ADHD, and Developmental Coordination Disorder DCD. This cross-sectional observational case-control study aims to better understand how these developmental disorders affect childrens growth, learning, communication, behavior, social skills, and motor abilities. The study follows STROBE guidelines and is conducted by the University of Vic - Central University of Catalonia, with ethical approvals in place to protect participants and their data. The study includes two groups children with typical neurodevelopment and children with atypical neurodevelopment diagnosed with ASD, ADHD, or DCD. Participants will be recruited from local communities and specialized centers. Motor skills will be assessed using the Movement Assessment Battery for Children-Second Edition MABC-2, while sensory processing will be evaluated through the Short Sensory Profile-2 SSP-2 caregiver questionnaire. Recruitment will occur from December 2024, with assessments and data collection performed according to the study protocol. Participants will be involved in assessments of motor development and sensory processing, including video-recorded sessions for motor skills evaluation. Researchers will collect demographic and developmental information from parents or guardians. The main outcome measured is motor skill development within one month of enrollment, with sensory processing also assessed during this time. Confidentiality and data protection are ensured, and participants may withdraw at any time. The study is expected to provide insights to help tailor future clinical and educational interventions for children with developmental differences.

Researchers are evaluating an integrated home care program called ADMIT for older adults aged 70 or more who live at home and face complex health and social needs. The study aims to see if this multi-component intervention, which uses technology and coordinated care, can increase the percentage of days these individuals spend at home compared to usual care. Additional goals include reducing health crises, improving quality of life for patients and their caregivers, and assessing the programs cost-effectiveness and overall experience. Participants will be randomly assigned to either receive usual care or the ADMIT program, which is co-created by professionals, patients, and caregivers. The ADMIT program involves proactive candidate detection from health and social services, assignment of reference professionals from both sectors, shared diagnosis and individualized care plans, and ongoing shared follow-up. A technological platform supports communication and information sharing among all parties, with optional use of sensors and robotic devices to assist home care. During the six-month intervention, researchers will track the percentage of days participants spend at home, monitor health and social crises, and gather feedback on experiences from patients, caregivers, and professionals. The study uses mixed methods to evaluate effectiveness, safety, and cost-utility in real-world settings, with an overall goal to support aging individuals in their homes while improving care quality and system sustainability.

Researchers are evaluating a digital health program designed to improve bladder health and manage urinary incontinence in adults aged 50 and over. This study involves co-creating a new module within the approved Keep-on-Keep-up KOKU app, developed with input from users, health professionals, and experts. The research includes a randomized controlled trial to test the programs feasibility and acceptability using behavior change techniques and addressing active and healthy aging policies. The study is organized into several phases, starting with protocol preparation and expert consultations, followed by multiple focus groups in Lithuania, Spain, and the UK to co-create the app module. After development, a 12-week intervention will be conducted with at least 120 participants across three countries, randomly assigned to either the KOKU Bladder app group or a control group receiving recommendations for self-managing urinary symptoms. Both groups will be assessed using qualitative and quantitative methods. Participants will engage in the trial for up to three years, during which their urinary incontinence symptoms, life impact, satisfaction with treatment, and bladder health will be regularly evaluated using questionnaires and tests such as the Incontinence Impact Questionnaire-7 and the International Prostate Symptom Score. Data collection includes thematic analysis of qualitative feedback and measurement of symptom severity and patient impressions. Safety and ethical considerations are integrated throughout, with plans for open communication and dissemination of results.