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Actively Recruiting

Researchers are evaluating new disease descriptions and management guidelines for breath-holding spells in children under 5 years old living in southern Sweden. The study aims to see if these guidelines reduce unnecessary diagnostic tests, ensure safe clinical management, and assess if iron supplementation lessens the frequency and severity of spells. It also explores the types of information and support parents need for children with these spells. Children diagnosed with typical breath-holding spells will be managed following the new guidelines. Those with a family history or signs of heart disease will receive an ECG, and children with two or more spells will have blood tests to check for anemia and iron deficiency. If iron deficiency is found, iron supplements are recommended. Digital surveys will be given to parents, and children with frequent spells may be invited to participate in interviews. Participants will undergo evaluations by medical doctors, with follow-up lasting up to 36 months to monitor safety and guideline use. The study will measure the safety of the guidelines over this period and usability shortly after inclusion. Researchers will also assess the usability of the disease definition until the doctors complete their assessments. Parents will provide information through surveys, and some may join interviews to share their experiences and support needs.

Age: 0Months - 60MonthsAll GendersPhase Not Applicable
12 locations
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Actively Recruiting

Researchers are studying the relationship between different levels of physical activity, sedentary time, and health outcomes in patients who have had a myocardial infarction (heart attack). The main goal is to understand how activity measured by accelerometers relates to clinical outcomes and how changes in physical activity over time affect these outcomes after a heart attack. The study plans to include about 4000 patients over two years who have experienced a myocardial infarction. Participants will wear an accelerometer device attached to their right hip during waking hours for seven consecutive days at two follow-up visits: once at 2 months and again at 1 year after hospital discharge. They will also keep a paper diary to record device wear time and working hours, then return both by mail. This process is repeated at the 1-year follow-up. During the study, participants attend follow-up visits where their physical activity data are collected and analyzed. Researchers will explore how different intensities of activity relate to major adverse cardiovascular events one year after the heart attack. Safety and adherence are monitored by collecting activity diaries and accelerometer data. Participation spans from hospital discharge through at least one year after the event to track outcomes and physical activity changes over time.

Age: 18Years - 79YearsAll Genders
35 locations
Simrishamn Clinical Trials | DecenTrialz