Simrishamn

Researchers are evaluating new disease descriptions and management guidelines for breath-holding spells in children under 5 years old in southern Sweden. The study aims to determine if these guidelines reduce unnecessary diagnostic procedures and are safe to use. It also investigates whether iron supplements decrease the frequency and severity of these spells and explores what information and support parents need for managing their childrens condition. Children diagnosed with typical breath-holding spells will be managed according to the new guidelines, which include cardiac evaluations like ECG for those with relevant family history or symptoms, and blood tests for anemia and iron deficiency if the child has multiple spells. Children with non-typical spells will be assessed individually using current practices. If iron deficiency is identified, supplementation is recommended. Some parents of children with frequent spells may participate in interviews as part of a sub-study. Participants will be evaluated by medical doctors and monitored through digital surveys over time. Researchers will assess the safety and usability of the guidelines, the effectiveness of iron treatment, and the support needs of parents. The study includes follow-up for up to 36 months to monitor outcomes and uses interviews and surveys to gather detailed information from families. The total participation duration varies, with specific assessments scheduled within weeks to months after inclusion.

Researchers are investigating how different levels of physical activity, measured objectively, relate to health outcomes in patients who have had a type 1 myocardial infarction. The study aims to explore links between activities of varying intensity, sedentary time, and the risk of major cardiovascular events after a heart attack, as well as how changes in physical activity over time affect these outcomes. Participants in this observational study will be asked to wear an accelerometer device on their right hip during waking hours for seven consecutive days at two follow-up visits2 months and 1 year after hospital discharge. They will also keep a diary recording their wear time and working hours if applicable. About 4000 patients aged 18 to 79 diagnosed with myocardial infarction are expected to be included, and the study will analyze the dose-response relationship between accelerometer data and clinical outcomes. Throughout the study, participants will attend cardiac rehabilitation follow-up visits and provide accelerometer and diary data. Researchers will assess outcomes such as major adverse cardiovascular events, including heart failure, stroke, death, and coronary revascularization, at 1 and 3 years after the initial cardiac event. The study will monitor these outcomes while participants continue their usual care, with a total follow-up period extending to 3 years after the heart attack.