Pingtung City

Researchers are evaluating the effects of liquid vitamin C and glutathione supplements on improving human skin condition and reducing oxidative stress. This trial is a single-center, placebo-controlled, double-blinded, parallel study involving healthy adults aged 18 to 65 years. The study aims to assess changes in skin beauty and antioxidant markers over a 12-week period. Participants will be randomly assigned to receive either a vitamin C and glutathione liquid sachet or a placebo sachet. Each participant is instructed to consume one sachet daily for 12 consecutive weeks. The trial includes baseline measurements before starting the supplement and follow-up assessments at 4, 8, and 12 weeks. Blood samples will be collected at the beginning and end of the study to evaluate antioxidant levels. Throughout the study, participants will undergo skin measurements and complete self-assessment questionnaires to monitor skin tone, spots, UV spots, hydration, redness, melanin index, elasticity, brown spots, wrinkles, texture, and collagen density. Researchers will also measure antioxidant capacity and related enzymes from blood samples. The total participation duration is 12 weeks, during which safety and effectiveness of the supplements will be monitored.