Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
ID07379216

Efficacy Evaluation Study of Vitamin C and Glutathione Liquid Sachet for Skin Condition and Anti-Oxidative Stress

Led by TCI Co., Ltd. · Updated on 2026-02-04

30

Participants Needed

1

Research Sites

2 weeks

Total Duration

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AI-Summary

What this Trial Is About

Researchers are evaluating the effects of liquid vitamin C and glutathione supplements on improving human skin condition and reducing oxidative stress. This trial is a single-center, placebo-controlled, double-blinded, parallel study involving healthy adults aged 18 to 65 years. The study aims to assess changes in skin beauty and antioxidant markers over a 12-week period. Participants will be randomly assigned to receive either a vitamin C and glutathione liquid sachet or a placebo sachet. Each participant is instructed to consume one sachet daily for 12 consecutive weeks. The trial includes baseline measurements before starting the supplement and follow-up assessments at 4, 8, and 12 weeks. Blood samples will be collected at the beginning and end of the study to evaluate antioxidant levels. Throughout the study, participants will undergo skin measurements and complete self-assessment questionnaires to monitor skin tone, spots, UV spots, hydration, redness, melanin index, elasticity, brown spots, wrinkles, texture, and collagen density. Researchers will also measure antioxidant capacity and related enzymes from blood samples. The total participation duration is 12 weeks, during which safety and effectiveness of the supplements will be monitored.

CONDITIONS

Brief Title

Efficacy Evaluation Study of Vitamin C and Glutathione Liquid Sachet

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy male or female adults aged 18 to 65 years
  • Commitment not to use products with similar activity to the test supplements during the study
  • Free of any skin or systemic disorders that could affect study results
Not Eligible

You will not qualify if you...

  • Obvious skin surface damage
  • Use of oral or topical medications affecting skin within 1 month
  • Known allergies to cosmetics, medications, foods, especially legumes or soy
  • Pregnant or breastfeeding individuals
  • Received facial laser therapy or chemical peeling within the past 2 months
  • Unwilling to allow publication or public disclosure of study photographs

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 12 weeks

Participants consume 1 sachet of the test samples daily for 12 consecutive weeks. Skin measurements and self-assessment questionnaires are conducted at baseline, and after 4, 8, and 12 weeks of consumption. Fasting blood samples are collected at baseline and after 12 weeks.

4 visits (in-person) including baseline and follow-ups at weeks 4, 8, and 12

Trial Site Locations

Total: 1 location

1

Chia Nan University of Pharmacy & Science

Pingtung City, Taiwan, 928

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Research Team

C

Chia-Hua Liang, Ph.D.

P

Ping Lin

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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