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Actively Recruiting

Researchers are working to create and test a model that predicts the size of a quadrupled rectus femoris tendon graft used in anterior cruciate ligament (ACL) reconstruction surgery. The graft diameter is important because smaller grafts have been linked to higher failure rates. Unlike hamstring tendon grafts, there is currently no validated model for predicting rectus femoris graft size. The study will analyze data from patients who have undergone ACL reconstruction with rectus femoris tendon autografts. By looking at patient body measurements and tendon specifics collected during surgery, the researchers will develop a predictive formula using statistical methods. The model will then be tested to see how well it can identify graft sizes that are clinically sufficient, such as 8 mm or 9 mm in diameter. Participants will be patients aged 18 or older having primary ACL reconstruction with rectus femoris tendon grafts and complete data available. The main measure is the measured graft diameter. Data may be collected prospectively or retrospectively. The study aims to improve preoperative planning and surgical decisions by providing a reliable way to estimate graft size before surgery.

Age: 18Years +All Genders
1 location
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Actively Recruiting

Researchers are evaluating and comparing two pain relief methods—the serratus posterior superior intercostal plane block and intrathecal morphine—in adults undergoing video-assisted thoracoscopic surgery. This prospective, randomized, controlled, single-center clinical trial includes patients aged 18 to 75 years with physical status I to III who are scheduled for elective thoracoscopic procedures such as wedge resection, segmentectomy, or lobectomy. The goal is to determine how these two techniques differ in managing postoperative pain. Participants will be randomly assigned to receive either the serratus posterior superior intercostal plane block or intrathecal morphine before general anesthesia. The intercostal plane block is performed under ultrasound guidance with an injection of bupivacaine and epinephrine, while intrathecal morphine involves a spinal injection of morphine diluted in saline at the lumbar level. All patients will then undergo standardized general anesthesia and receive patient-controlled analgesia after surgery. During the study, researchers will monitor opioid use during the first 24 hours after surgery, measuring total morphine equivalents. They will also assess pain scores at rest and with activity, time to first request for pain medication, recovery quality, and any postoperative complications including nausea, sedation, itching, respiratory depression, and other issues up to 30 days after surgery. These assessments aim to improve postoperative pain management in thoracic surgery patients.

Age: 18Years - 75YearsAll GendersPhase Not Applicable
1 location
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