Tunceli Merkez

Type 2 Diabetes Mellitus T2DM is a chronic condition involving insulin resistance and sustained high blood sugar levels that affect not only metabolism but also brain function, autonomic nervous system, heart regulation, cognition, and mental health. People with T2DM face increased risks of cognitive decline, autonomic dysfunction, reduced physical capacity, and psychological distress. This study investigates how metabolic problems relate to brain and heart function in adults with T2DM, focusing on the connections between brain activity, heart rate variability, cognition, physical function, and mental well-being. About 50 adults aged 40 to 65 with confirmed T2DM will participate in this observational cross-sectional study. Participants will undergo comprehensive assessments during a single visit, including resting electroencephalography EEG to measure brain activity, heart rate variability HRV to assess autonomic heart regulation, functional tests like the 1-Minute Sit-to-Stand and 6-Minute Walk, cognitive evaluation using the Montreal Cognitive Assessment, physical activity questionnaires, and psychological assessments with the Depression Anxiety Stress Scale and Hospital Anxiety and Depression Scale. Clinical data such as blood sugar control, lipid levels, and inflammation markers will be collected from medical records. Participants will complete all assessments in approximately one 60-minute visit. Researchers will analyze data to explore relationships between metabolic factors, brain and heart function, cognitive and physical performance, and mental health. The main outcomes include EEG brain wave measurements and HRV parameters. The study aims to improve understanding of neurocardiac function in T2DM and help develop better strategies for early detection of brain-heart dysfunction and tailored rehabilitation.

Researchers are evaluating the effects of long-term rowing training on aerobic capacity, physical fitness, heart rate variability, and psychological performance in adults with different levels of rowing experience. This study compares novice rowers, professional rowers, and healthy controls to understand how an 8-week rowing program influences physiological and psychological adaptations. Participants in the novice and professional rowing groups will complete supervised rowing ergometer training sessions twice weekly for 8 weeks. Novice rowers will focus on moderate-intensity exercise emphasizing technical skill development, while professional rowers will engage in higher-intensity interval and race-pace training. The control group will maintain usual activities without structured exercise. Assessments will be done before and after the intervention period. Throughout the study, participants will undergo tests measuring aerobic capacity, muscle strength, power, endurance, core stability, flexibility, agility, posture, and heart rate variability using a chest-strap monitor. Psychological performance will be assessed through flow state and mental toughness questionnaires. The study aims to provide a detailed evaluation of training effects and support improved training strategies for rowers. Total participation lasts 8 weeks with evaluations at baseline and after training.

Researchers are evaluating the effects of education on patients who have undergone stoma surgery, such as colostomy or ileostomy. This study focuses on how education impacts stoma adaptation, body image, and self-efficacy. Stomas are commonly created for various gastrointestinal conditions, including colorectal cancer and inflammatory bowel diseases, but complications and challenges can affect patients quality of life. The study aims to address these issues by improving patients knowledge and skills through education. The study compares two groups one receiving stoma care education using the Teach-Back method, a nursing behavioral intervention, and the other receiving standard clinical training without additional education. No drugs or devices are used. Education programs cover essential topics like nutrition, elimination, sexuality, social participation, and privacy to help prevent complications and improve self-care. Participants will be assessed at multiple time points post-surgery day 2, discharge day days 7-10, one month after discharge, and three months after discharge. Researchers will measure stoma adjustment as the primary outcome, with body image and self-efficacy as secondary outcomes. The study includes regular follow-ups to monitor these factors and support participants adaptation over time.

Hypertension is linked to problems with the autonomic nervous system, reduced muscle strength, and lower functional capacity, which increase cardiovascular risks and reduce quality of life. This trial evaluates the differences between unilateral one limb at a time and bilateral both limbs together resistance training on heart rate variability HRV, muscle strength, and functional capacity in adults with hypertension aged 40 to 75 years. Participants will be randomly assigned to one of three groups unilateral resistance training, bilateral resistance training, or a control group. Those in the training groups will complete a supervised 12-week program, exercising twice weekly at 60-70% of their one-repetition maximum. Exercises include leg press, knee extension, leg curl, seated row, and chest press. The control group will receive general physical activity education without supervised training. Participants will undergo assessments before and after the 12-week period. HRV will be measured with a Polar H10 heart rate sensor and analyzed using Elite HRV software. Muscle strength will be tested with one-repetition maximum methods, functional capacity with the Six-Minute Walk Test and Glittre Activities of Daily Living Test, and blood pressure with a sphygmomanometer. Researchers aim to identify which training method best improves autonomic function and physical performance in hypertension.