Eynsham

Researchers are conducting a prospective observational study to evaluate the health of multiple organs using multiparametric abdominal magnetic resonance imaging (MRI) in adults with type 2 diabetes who have no history of cardiovascular disease. The study aims to determine if MRI metrics can predict future clinical events over five years, focusing on cardiovascular outcomes such as heart attacks, strokes, and hospitalizations. Participants will not receive any new treatments as part of this study; instead, they will undergo standard care and two study visits. The first visit involves physical measurements and collection of blood and urine samples to assess diabetes status and biomarkers. The second visit includes a multi-organ MRI scan. Both visits occur within 28 days of the initial screening, which includes medical review and informed consent. During the five-year participation, researchers will collect MRI data, clinical outcomes, blood and urine samples, and access medical records from NHS England and local healthcare providers. Follow-up data on hospital admissions and mortality will be gathered at 1, 3, and 5 years after the baseline assessment. The primary outcome is the incidence of major cardiovascular events over three years based on baseline MRI findings.