New London

Researchers are studying individuals with generalized stage III periodontitis to compare the safety and healing effects of a new periodontal hydrogel dressing called Emanate Perio PODS. This device is being evaluated to see if it improves wound healing after plaque and tartar removal from teeth compared to no treatment. The study focuses on the critical healing period following non-surgical periodontal therapy and aims to protect healing tissue from harmful bacteria. The trial involves two groups one group uses the Emanate Perio PODS device twice daily for 30 minutes each session for 15 days after scaling and root planing SRP, while the other group receives no additional treatment after SRP. The dressing is applied immediately after toothbrushing and interdental cleaning to shield the healing periodontal pocket during the first 30 days post-treatment, especially during the initial phases when the tissue is vulnerable. Participants will be monitored over 60 days after their non-surgical therapy. Researchers will assess healing by checking for gingival bleeding and other signs of wound repair. The study includes regular periodontal evaluations, intraoral digital scans, and requires participants to follow oral hygiene instructions carefully. The goal is to evaluate the effectiveness and safety of the dressing in supporting tissue healing after SRP with minimal burden on participants.

Researchers are studying women undergoing surgical repair of pelvic organ prolapse to evaluate how effective postoperative sitz baths are in managing pain and aiding recovery. This prospective, randomized controlled trial, called the SORE Study, compares the pain intensity reported one week after native tissue repair between patients using a sitz bath regimen and those receiving usual care. The study also aims to explore patient satisfaction with pain management, opioid use, healthcare visits, adherence to pain plans, and healing complications. Participants are assigned to one of two groups one group uses warm water sitz baths nightly for seven days after surgery along with usual care, while the other group receives usual care without sitz baths. The sitz bath involves soaking in warm water for 10 minutes each night. The study begins soon after surgery and includes a week of intervention and follow-up. Throughout the study, participants will complete questionnaires about their pain levels and satisfaction with pain management on day 7 after surgery. Researchers will track opioid use, adherence to the sitz bath regimen, any barriers to its use, rare adverse effects, and the number of calls or emergency visits related to pain up to 90 days after surgery. The total participation duration includes the initial week of treatment and monitoring up to 90 days for safety and healthcare use.