Old Saybrook

Researchers are studying basivertebral nerve ablation (BVNA), a minimally invasive procedure for vertebrogenic low back pain. The study focuses on understanding how pain relief and functional improvement change over time after BVNA, as well as identifying early factors that might predict a positive clinical response. The trial aims to better evaluate real-world outcomes beyond initial studies supporting BVNA's effectiveness. Participants will undergo fluoroscopically guided intraosseous BVNA using the Intracept System targeting specific vertebral endplate changes seen on MRI. The procedure involves thermal radiofrequency ablation delivered under general anesthesia through precise probe placement. Treatment targets only vertebral levels with confirmed Modic changes. Patient-reported outcomes will be collected weekly for 8 weeks and then at multiple follow-up visits up to 2 years. Participants will attend a total of 11 visits including one baseline, eight weekly virtual or phone visits, and in-person or virtual visits at 3, 6, 12, and 24 months. Researchers will assess clinical response defined by pain and disability improvements, changes in patient-reported measures, and the need for further interventions like injections or surgery. Safety and adverse events will also be monitored throughout the study duration.