Winder

Researchers are evaluating the performance of two blood-based diagnostic tests designed to help detect cancer in individuals aged 45 and older who show symptoms, signs, or findings that suggest cancer. The study aims to assess these tests in people suspected of having cancer or those recently diagnosed but not yet treated. This observational study is sponsored by Harbinger Health and focuses on cancers originating from specific sites outlined in the study protocol. Participants will provide a blood sample of up to 40 mL collected in special tubes for analysis by the investigational diagnostic tests. Those with suspected cancer will undergo a standard diagnostic work-up to confirm if cancer is present, while those already diagnosed must be treatment-nave. The results of the diagnostic tests will not be shared with patients or doctors and will not influence clinical decisions. All testing and analyses are conducted in a blinded manner. During the study, participants will complete a blood draw and follow the usual diagnostic procedures as needed. Researchers will track clinical outcomes, diagnostic test performance, and cancer incidence over 18 months. The main measure is how well the two diagnostic tests identify cancer among participants showing relevant symptoms or signs. Safety and adherence will be monitored, but the study does not involve treatment. Total participation duration may vary depending on diagnostic and follow-up processes.

Researchers are evaluating a web-based Mindfulness-Based Relapse Prevention MBRP continuing care program called Renewed Recovery for individuals with Alcohol Use Disorder AUD who are exiting standard outpatient treatment. This pilot study follows a structured five-step framework guided by the Centre for eHealth and Wellbeing Research roadmap to design, implement, and assess the interventions impact on supporting recovery and reducing relapse risk. The intervention consists of an eight-week self-guided online curriculum with weekly modules that include educational content, mindfulness exercises, and videos. Participants attend two live group meditation sessions via Zoom during weeks 3 and 6. Before launching the pilot, the website and program are refined based on feedback from stakeholders and usability testing. The pilot will be conducted with 30 participants recruited from partnering treatment facilities. Participants will complete surveys at the start, end, and three months after the program to measure alcohol consumption and other outcomes such as depression, anxiety, coping behaviors, cravings, mindfulness, acceptance, self-efficacy, triggers, and social support. Additional evaluations include program and website satisfaction, recruitment and retention rates, and focus groups. The study aims to understand the usability and effectiveness of this digital continuing care option for AUD recovery.