Baldwin

Researchers are evaluating different ways to deliver talk therapy for adults with posttraumatic stress disorder (PTSD) who receive care at federally qualified health centers. The study aims to find out if starting with one type of therapy is more effective than another, and whether switching to a different therapy after four sessions helps more than continuing the same therapy, based on how well the treatment is working early on. This approach seeks to reduce PTSD symptoms while using resources efficiently. Participants may receive one of several therapies: Prolonged Exposure for Primary Care (PE-PC), which includes four weekly 30-minute sessions with exposure exercises to help face trauma reminders; Full Prolonged Exposure therapy, consisting of eight weekly 60-minute sessions with in vivo, imaginal, and emotional exposure plus daily home practice; or a brief psychotherapy supported by a PTSD Coach mobile app developed by the study team that offers assessment, education, and self-management strategies. After initial sessions, some participants may reduce therapy frequency depending on their response. During the study, participants' PTSD symptoms will be measured using a clinician-administered scale at the start and three months later. The study tracks symptom changes and therapy effectiveness while monitoring participant safety and treatment adherence. The total participation duration includes baseline and follow-up assessments to evaluate how symptoms improve with these adaptive therapy approaches.