Klamath Falls

Researchers are evaluating the immediate effects of three different doses of a probiotic strain called Bacillus coagulans JBI-YZ6.3 BC4U on immune function compared to a placebo. This clinical proof-of-concept study involves 24 healthy adult participants aged 18 to 75 years. The goal is to understand how the probiotic influences immune status and cytokine levels shortly after intake. Participants will take placebo and three escalating doses of the probiotic 0 mg placebo, 100 mg, 200 mg, and 400 mg each during separate clinic visits spaced at least one week apart for washout. At each visit, blood samples will be collected before the dose and again at 1, 2, and 3 hours after taking the probiotic or placebo. During the study, participants will undergo blood draws to assess immune communication, immune surveillance, cell activation, cell priming, and cytokine profiles. Researchers will monitor these immune responses up to 3 hours after dosing. The study requires participants to maintain consistent diet and lifestyle habits and involves multiple visits over the course of the trial ending in December 2025.

Researchers are evaluating the immediate effects of a nutritional blend on immune cells in a healthy adult population. This clinical trial uses a double-blind, placebo-controlled, cross-over design to compare the immune responses after consuming a nutraceutical blend versus a placebo. The nutraceutical blend contains low molecular weight peptides from cow colostrum ultrafiltrate, mushroom extracts, and vitamin C. Participants will consume either the active nutraceutical blend or a placebo in two separate clinic visits spaced at least one week apart to allow a washout period. Each dose consists of four capsules taken during each visit. The study design randomizes participants to receive the interventions in different orders to assess the rapid immune effects. During each visit, baseline blood samples are collected one hour after arrival, followed by administration of the test product. Additional blood samples are drawn one, two, and three hours after consumption to monitor immune cell surveillance and activation status. The total duration of participation spans approximately two weeks, including the washout period between visits. The study focuses on measuring immune cell changes three hours after product intake.

Researchers are evaluating the immediate immune effects of three medicinal mushroomsAgaricus blazei, Reishi, and Turkey Tailcompared to a placebo in healthy adults aged 18 to 75. The study focuses on how these mushrooms influence immune cell communication, including pro- and anti-inflammatory signals, immune cell alertness, and immune surveillance, which are natural parts of the bodys immune cycles. Participants take part in a crossover study where each person consumes one of the test mushroom products or a placebo on four separate clinic days, each at least one week apart to allow for a washout period. The mushroom capsules are given at a dose of 2000 mg per serving. The order in which participants receive the mushrooms and placebo varies among four different randomized groups over four weeks. During the study, participants undergo blood draws and other evaluations two hours after taking each test product to measure immune communication and immune cell surveillance. They follow specific routines including consistent diet and lifestyle habits, bland breakfasts before visits, and abstaining from exercise, certain beverages, and distractions during clinic visits. The study includes safety monitoring and lasts about four weeks in total, with each visit spaced to allow clear comparison between the mushrooms and placebo effects.

Researchers are evaluating the rapid effects of a non-transdermal biofield skin patch on antioxidant protection and cellular energy. This proof-of-concept clinical study uses a double-blind, placebo-controlled, randomized crossover design to compare an active biofield patch with a placebo patch. The study aims to measure changes in antioxidant activity, mitochondrial function, and inflammatory markers to understand the patchs impact on these biological processes. Participants will wear either the active biofield patch or a placebo patch for 12 hours during two separate clinic visits spaced at least one week apart, with a one-week washout period between visits. The order of patch use varies between two groups to ensure proper comparison. After this blinded phase, participants enter an open-label phase where they wear the active patch daily for one week before their final clinic visit. During the study, researchers will collect data on antioxidant enzymes, mitochondrial volume and membrane potential in white blood cells, and serum cytokine levels at baseline, one hour, and two hours after patch application. Participants will undergo multiple blood draws, and adherence to dietary and lifestyle guidelines will be monitored. The primary outcome focuses on antioxidant protection, with secondary outcomes assessing mitochondrial function. The total participation period spans multiple visits over several weeks, including the open-label extension.

Researchers are studying how four different dietary supplement products affect stem cells, immune activation, and mitochondrial function in healthy adults. This randomized, double-blind, placebo-controlled, crossover trial aims to document rapid changes in stem cell surveillance and mitochondrial resilience after consuming these products. The trial is designed to explore acute biological effects within a short timeframe after ingestion. Participants will take each of the four active test products and a placebo in a randomized order over five clinic visits spaced at least one week apart, allowing for a one-week washout between each. Each product and placebo are given as two capsules per visit. The study has four different crossover groups, each with a different order of product administration to compare effects systematically. During each clinic visit, participants will undergo multiple blood draws to measure stem cell trafficking and mitochondrial function in white blood cells at baseline and at 1, 2, and 3 hours after product ingestion. Researchers will assess mitochondrial volume and membrane potential under normal and stressed conditions. The entire study spans approximately five weeks with careful monitoring of diet, exercise, and supplement intake to maintain consistency and accuracy of results.