Klamath Falls

Researchers are evaluating the immediate effects on the immune system of three different doses of a probiotic strain called Bacillus coagulans JBI-YZ6.3 (BC4U) compared to a placebo. This clinical proof-of-concept study involves 24 healthy adult participants aged 18 to 75 years. The focus is on understanding how the probiotic influences immune surveillance, immune cell activation, priming, and cytokine levels. Participants will take placebo and three escalating doses of the probiotic (0 mg, 100 mg, 200 mg, and 400 mg) in a cross-over design. Each treatment is given on separate clinic visits, spaced by a one-week washout period. Blood samples will be taken multiple times: 1 hour after arrival before dosing, and then 1, 2, and 3 hours after administration to assess the acute immune response. Throughout the study, participants will maintain consistent diet and lifestyle routines, including bland breakfasts and avoiding exercise, supplements, coffee, tea, and soft drinks around visit times. Researchers will measure immune communication and various immune panels during the three hours following dosing. Multiple blood draws will be performed, with safety and adherence closely monitored during the study period.

Researchers are investigating the immediate effects of a nutritional blend on immune cells in healthy adults aged 18 to 75. This clinical trial uses a randomized, double-blind, placebo-controlled, cross-over design to compare the immune response after consuming a nutraceutical blend versus a placebo. The nutraceutical blend contains low molecular weight peptides from cow colostrum ultrafiltrate, mushroom extracts, and vitamin C. Participants will consume either four capsules of the nutraceutical blend or four capsules of placebo during each study period, with a one-week washout between treatments. Blood samples will be collected at baseline (one hour after arrival), and then at one, two, and three hours after taking the test product to monitor changes in immune cells. Throughout the study, participants will follow specific guidelines such as maintaining a consistent diet and lifestyle, avoiding exercise and supplements on study mornings, and not consuming coffee, tea, or soft drinks at least one hour before visits. The main outcome measured is immune cell surveillance three hours after product consumption. The study involves 24 participants with multiple blood draws to monitor immune responses over time.

Researchers are evaluating the rapid immune effects of three different medicinal mushrooms—Agaricus, Reishi, and Turkey Tail—compared to a placebo in healthy adults aged 18 to 75 years. The study focuses on how these mushrooms may influence immune cell communication, including pro- and anti-inflammatory signals, increased immune cell alertness, and immune cell movement and surveillance, which are naturally part of the body's daily immune cycles. Participants will take capsules containing 2000 mg of one of the mushrooms or a placebo. The study compares these interventions to observe their immediate effects on the immune system. Multiple blood draws will be performed to monitor immune responses shortly after consumption of the test product. During the study, participants will be asked to maintain consistent diet and lifestyle habits, follow restrictions such as avoiding exercise, nutritional supplements, coffee, tea, and soft drinks before visits, and refrain from distractions during clinic visits. The main outcome measured is immune communication assessed two hours after taking the test product. The study includes careful monitoring throughout the visits to understand the mushrooms' impact on immune surveillance.

Researchers are investigating the immediate effects of a special biofield skin patch compared to a placebo patch on antioxidant and mitochondrial functions. This clinical proof-of-concept study uses a double-blind, placebo-controlled cross-over design to evaluate changes in antioxidant protection and cellular energy in healthy adults aged 18 to 75 years. The study aims to see if the active patch influences antioxidant activity, mitochondrial resilience, and inflammatory markers in blood cells under both normal and stressed conditions. Participants will receive both an active non-transdermal dermal patch and a placebo patch in a randomized order, without knowing which one they are wearing. After the initial testing phases, an additional open-label period involves wearing the active patch daily for a week before the final clinic visit. This design allows comparison of the patch's acute effects and any changes after repeated daily use. During the study, researchers will collect blood samples and measure antioxidant protection at baseline, and one and two hours after applying the patch. They will also evaluate mitochondrial function and cytokine levels in the blood and extracellular vesicles. Participants must follow specific dietary and lifestyle guidelines during clinic visits to ensure consistent testing conditions. Safety and adherence will be monitored throughout the study, which includes multiple blood draws and clinic visits.

This clinical trial investigates the immediate effects of consuming four different dietary products on stem cells, immune system activation, and the function of mitochondria, which are the energy producers in cells. The study uses a double-blind, placebo-controlled, cross-over design to compare these products and document any rapid changes in stem cell activity and mitochondrial resilience. The goal is to understand how these products might influence stem cell surveillance and cellular energy production under both normal and stressed conditions. Participants will consume one of five treatments during each study period: placebo, Chaga mushroom capsules, ginseng extract capsules, olive extract capsules, and potassium hydrogen glucarate capsules. Each treatment involves taking two capsules. The study design allows each participant to receive all products in a random order over different visits to compare effects fairly. This acute trial focuses on short-term responses shortly after product ingestion. During the study visits, researchers will collect blood samples at baseline and at 1, 2, and 3 hours after taking the study product to measure stem cell trafficking and mitochondrial function in white blood cells. Participants will be asked to maintain consistent diet and lifestyle habits, including bland breakfasts on visit days, and avoid exercise, supplements, coffee, tea, soft drinks, music, candy, gum, and electronic device use during visits. The main outcome measured is the movement of stem cells in the blood shortly after product consumption, along with assessments of mitochondrial energy production and resilience under oxidative and inflammatory stress. The study includes healthy adults aged 18 to 75 years with specific body mass index and vein visibility requirements.