Long-Covid-19 Alleviation Through Learning Mindfulness Study (LONG-CALM)

What this Trial Is About

Researchers are evaluating a mindfulness intervention for people experiencing symptoms of Post-Acute Sequelae of SARS-CoV-2 infection (PASC), commonly known as Long COVID. This study aims to determine if mindfulness, defined as paying attention to the present moment with acceptance and without judgment, can help reduce stress, lessen Long COVID symptoms, and improve quality of life. Mindfulness-Based Interventions have been shown in other studies to reduce stress in various populations, suggesting potential benefits for those with PASC. The study involves an 8-week online mindfulness program consisting of recorded sessions specifically developed for people with PASC. Participants are randomly assigned to either receive the mindfulness intervention immediately along with their usual medical care or to start the intervention eight weeks after enrollment while continuing their regular treatment. All participation is remote, with no in-person visits. Participants will complete four online surveys over six months to assess symptoms and quality of life. The main outcome measured is the Patient-Reported Outcomes Measurement Information System (PROMIS) Global 10 Score at two months. Additional assessments include symptom scores related to PASC, depression, anxiety, stress impact, and mindfulness during physical activity. The total study duration is six months, with all data collected remotely to monitor changes over time.

Long-Covid-19 Alleviation Through Learning Mindfulness Study