Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT07056348

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

Led by Jorge Gonzalez-Martinez · Updated on 2025-12-16

60

Participants Needed

1

Research Sites

451 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to recruit patients already implanted with Deep Brain Stimulation (DBS) for movement disorders to complete tasks assessing parameters of motor output, speech, and swallowing functions, both with and without stimulation. DBS parameters would be adjusted prior to motor testing. Patients would then participate in multiple sessions performing contralateral upper extremity movement tasks measuring movement speed, grip strength, and strength modulation, facial movement, swallowing, and speech tasks.

CONDITIONS

Official Title

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Movement disorder patients aged 18 years and older but younger than 80 years who have a DBS implant for motor symptom treatment
  • Provided written informed consent and HIPAA authorization before study procedures
Not Eligible

You will not qualify if you...

  • History of seizure disorders
  • History of vasovagal responses or loss of consciousness
  • Severe behavioral or cognitive problems affecting study participation
  • Serious illnesses like cancer, severe cardiac or respiratory disease, other neurological conditions besides current movement disorder, or cognitive impairments
  • Pregnant or breastfeeding females

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

C

Cierra Clark, MS

CONTACT

E

Elvira Pirondini, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function | DecenTrialz