Limitations of current antiretroviral agents and opportunities for development.
R Jain, N M Clark, M Diaz-Linares...
https://pubmed.ncbi.nlm.nih.gov/16515486Completed
Age: 13Years +
All Genders
ID00001137
Adult AIDS Clinical Trials Group Longitudinal Linked Randomized Trials (ALLRT) Protocol
Led by Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · Updated on 2013-12-06
5982
Participants Needed
77
Research Sites
N/A
Total Duration
On this page
Sponsors
A
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Lead Sponsor
N
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to determine what combinations of anti-HIV drugs work best in patients treated over several years. The study will also assess the occurrence of side effects and opportunistic infections in patients with low viral loads compared to those with higher viral loads.
CONDITIONS
Official Title
Long-Term Data Collection From Participants in Adult AIDS Clinical Trials
Who Can Participate
Age: 13Years +
All Genders
Eligibility Criteria
You may qualify if you...
Inclusion Criteria
- HIV-1 infected
- Enrolled in an AIDS Clinical Trial Group (ACTG) parent study and has enrolled in this study on or before the Week 16 visit of the parent study, including the visit window of the parent study. More information on this criterion can be found in the protocol.
- Willing to provide consent for the release and use of clinical data from the parent study
- Life expectancy of at least 24 weeks
- Parent or guardian willing to provide informed consent, if applicable
Exclusion Criteria
- Active alcohol or drug abuse that may interfere with the study
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 77 locations
1
Univ of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
Status Unknown
2
Kaiser Permanente LAMC
Los Angeles, California, United States, 90027
Status Unknown
3
Univ of Southern California / LA County USC Med Ctr
Los Angeles, California, United States, 900331079
Status Unknown
4
UCLA CARE Ctr
Los Angeles, California, United States, 90095
Status Unknown
5
Willow Clinic
Menlo Park, California, United States, 94025
Status Unknown
6
UC Davis Med Ctr
Sacramento, California, United States, 95814
Status Unknown
7
Univ of California / San Diego Treatment Ctr
San Diego, California, United States, 921036325
Status Unknown
8
Univ of California, San Francisco/San Francisco General Hosp
San Francisco, California, United States, 94110
Status Unknown
9
Santa Clara Valley Med Ctr / AIDS Community Rsch Consortium
San Jose, California, United States, 951282699
Status Unknown
10
Marin County Specialty Clinic
San Rafael, California, United States, 94903
Status Unknown
11
San Mateo AIDS Program / Stanford Univ
Stanford, California, United States, 943055107
Status Unknown
12
Stanford Univ Med Ctr
Stanford, California, United States, 943055107
Status Unknown
13
Harbor UCLA Med Ctr
Torrance, California, United States, 90502
Status Unknown
14
Denver Public Health CRS
Denver, Colorado, United States, 80204
Status Unknown
15
Univ of Colorado Health Sciences Ctr
Denver, Colorado, United States, 80262
Status Unknown
16
Georgetown Univ Med Ctr
Washington D.C., District of Columbia, United States, 20007
Status Unknown
17
Univ of Miami School of Medicine
Miami, Florida, United States, 331361013
Status Unknown
18
Emory Univ
Atlanta, Georgia, United States, 30308
Status Unknown
19
Emory Hemo Comp Evaluation Clinic / East TN Comp Hemo Ctr
Atlanta, Georgia, United States, 303652225
Status Unknown
20
Univ of Hawaii
Honolulu, Hawaii, United States, 96816
Status Unknown
21
Tripler Army Med Ctr
Tripler AMC, Hawaii, United States, 96859
Status Unknown
22
Northwestern Univ Med School
Chicago, Illinois, United States, 60611
Status Unknown
23
Cook County Hosp
Chicago, Illinois, United States, 60612
Status Unknown
24
Rush Presbyterian - Saint Luke's Med Ctr
Chicago, Illinois, United States, 60612
Status Unknown
25
Indiana Univ Hosp
Indianapolis, Indiana, United States, 462025250
Status Unknown
26
Division of Inf Diseases/ Indiana Univ Hosp
Indianapolis, Indiana, United States, 46202
Status Unknown
27
Methodist Hosp of Indiana / Life Care Clinic
Indianapolis, Indiana, United States, 46202
Status Unknown
28
Univ of Iowa Hosp and Clinic
Iowa City, Iowa, United States, 52242
Status Unknown
29
Tulane Med Ctr Hosp
New Orleans, Louisiana, United States, 70112
Status Unknown
30
IHV Baltimore Treatment CRS
Baltimore, Maryland, United States, 21201
Status Unknown
31
Johns Hopkins Hosp
Baltimore, Maryland, United States, 21287
Status Unknown
32
Harvard (Massachusetts Gen Hosp)
Boston, Massachusetts, United States, 02114
Status Unknown
33
Brigham and Women's Hosp
Boston, Massachusetts, United States, 02115
Status Unknown
34
Boston Med Ctr
Boston, Massachusetts, United States, 02118
Status Unknown
35
Beth Israel Deaconess - West Campus
Boston, Massachusetts, United States, 02215
Status Unknown
36
Wayne State Univ. CRS
Detroit, Michigan, United States, 48201
Status Unknown
37
Hennepin County Medical Clinic
Minneapolis, Minnesota, United States, 55415
Status Unknown
38
Univ of Minnesota
Minneapolis, Minnesota, United States, 55455
Status Unknown
39
St Louis Regional Hosp / St Louis Regional Med Ctr
St Louis, Missouri, United States, 63112
Status Unknown
40
Univ of Nebraska Med Ctr
Omaha, Nebraska, United States, 681985130
Status Unknown
41
Cooper Univ. Hosp. CRS
Camden, New Jersey, United States, 08103
Status Unknown
42
New Jersey Medical School- Adult Clinical Research Ctr. CRS
Newark, New Jersey, United States, 07103
Status Unknown
43
SUNY / Erie County Med Ctr at Buffalo
Buffalo, New York, United States, 14215
Status Unknown
44
Beth Israel Med Ctr
New York, New York, United States, 10003
Status Unknown
45
Bellevue Hosp / New York Univ Med Ctr
New York, New York, United States, 10016
Status Unknown
46
NY Univ. HIV/AIDS CRS
New York, New York, United States, 10016
Status Unknown
47
Aaron Diamond AIDS Rsch Ctr / Rockefeller Univ
New York, New York, United States, 10021
Status Unknown
48
Chelsea Ctr
New York, New York, United States, 10021
Status Unknown
49
Cornell Univ Med Ctr
New York, New York, United States, 10021
Status Unknown
50
Mount Sinai Med Ctr
New York, New York, United States, 10029
Status Unknown
51
Columbia Presbyterian Med Ctr
New York, New York, United States, 10032
Status Unknown
52
AIDS Care CRS
Rochester, New York, United States, 14607
Status Unknown
53
Community Health Network Inc
Rochester, New York, United States, 14642
Status Unknown
54
Univ of Rochester Medical Center
Rochester, New York, United States, 14642
Status Unknown
55
Bronx-Lebanon Hosp. Ctr. CRS
The Bronx, New York, United States, 10457
Status Unknown
56
Wake County Department of Health
Chapel Hill, North Carolina, United States, 27514
Status Unknown
57
Univ of North Carolina
Chapel Hill, North Carolina, United States, 275997215
Status Unknown
58
Carolinas Med Ctr
Charlotte, North Carolina, United States, 28203
Status Unknown
59
Duke Univ Med Ctr
Durham, North Carolina, United States, 27710
Status Unknown
60
Moses H Cone Memorial Hosp
Greensboro, North Carolina, United States, 27401
Status Unknown
61
Univ of Cincinnati
Cincinnati, Ohio, United States, 452670405
Status Unknown
62
Cleveland Clinic
Cleveland, Ohio, United States, 44106-5083
Status Unknown
63
MetroHealth Med Ctr
Cleveland, Ohio, United States, 441091998
Status Unknown
64
Ohio State Univ Hosp Clinic
Columbus, Ohio, United States, 432101228
Status Unknown
65
The Research & Education Group-Portland CRS
Portland, Oregon, United States, 97210
Status Unknown
66
Presbyterian Medical Center - Univ. of PA
Norristown, Pennsylvania, United States, 19401
Status Unknown
67
Univ of Pennsylvania at Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Status Unknown
68
Univ of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Status Unknown
69
Julio Arroyo
West Columbia, South Carolina, United States, 29169
Status Unknown
70
Vanderbilt Univ Med Ctr
Nashville, Tennessee, United States, 37203
Status Unknown
71
Peabody Health Center CRS
Dallas, Texas, United States, 75215
Status Unknown
72
Univ of Texas, Southwestern Med Ctr of Dallas
Dallas, Texas, United States, 75390
Status Unknown
73
Houston AIDS Research Team CRS
Houston, Texas, United States, 77030
Status Unknown
74
Virginia Commonwealth Univ. Medical Ctr. CRS
Richmond, Virginia, United States, 23219
Status Unknown
75
Univ of Washington
Seattle, Washington, United States, 98104
Status Unknown
76
Puerto Rico-AIDS CRS
San Juan, Puerto Rico, 00935
Status Unknown
77
Univ of Puerto Rico
San Juan, Puerto Rico, 009365067
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Mohammed Siddiqui, T J Moore, Dustin M Long...
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Konstantia Angelidou, Peter W Hunt, Alan L Landay...
https://pubmed.ncbi.nlm.nih.gov/29309629Impact of aging on neurocognitive performance in previously antiretroviral-naive HIV-infected individuals on their first suppressive regimen.
Hamza Coban, Kevin Robertson, Marlene Smurzynski...
https://pubmed.ncbi.nlm.nih.gov/28471765Continued Slow Decay of the Residual Plasma Viremia Level in HIV-1-Infected Adults Receiving Long-term Antiretroviral Therapy.
Sharon A Riddler, Evgenia Aga, Ronald J Bosch...
https://pubmed.ncbi.nlm.nih.gov/26333941Patterns of peripheral neuropathy in ART-naïve patients initiating modern ART regimen.
Anthony J Lee, Ronald J Bosch, Scott R Evans...
https://pubmed.ncbi.nlm.nih.gov/25678143HIV-1 DNA decay dynamics in blood during more than a decade of suppressive antiretroviral therapy.
Guillaume J Besson, Christina M Lalama, Ronald J Bosch...
https://pubmed.ncbi.nlm.nih.gov/25073894Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment.
Allan R Tenorio, Yu Zheng, Ronald J Bosch...
https://pubmed.ncbi.nlm.nih.gov/24795473Impact of chemotherapy for HIV-1 related lymphoma on residual viremia and cellular HIV-1 DNA in patients on suppressive antiretroviral therapy.
Anthony R Cillo, Supriya Krishnan, Deborah K McMahon...
https://pubmed.ncbi.nlm.nih.gov/24638072