Actively Recruiting
Long-term Follow-up Study of Patients Receiving CAR-T Cells
Led by Medical College of Wisconsin · Updated on 2025-11-10
500
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research follows participants who have previously received CAR-T cells as part of clinical trials at the Medical College of Wisconsin and Froedtert Hospital. It aims to track long-term effects from 2 to 15 years after treatment, including the persistence of CAR-T cells, development of new cancers, and other medical issues. The follow-up covers patients treated for various blood cancers such as different types of lymphomas and multiple myeloma. Participants in this study do not receive any new treatments; instead, the study monitors those who have already undergone CAR-T cell therapy in earlier trials identified by their clinical trial numbers. The study observes participants over a long period, from 2 up to 15 years post-treatment, to assess ongoing health outcomes related to their CAR-T cell therapy. During the study, participants will undergo regular evaluations to detect any new malignancies and monitor the presence of CAR-T cells. The main measurements include tracking new cancer incidence at 5, 10, and 15 years after their initial treatment. This long-term observation helps researchers understand the lasting effects and safety of CAR-T cell therapies. Participation duration varies but extends up to 15 years post-treatment.
CONDITIONS
Brief Title
Long-term Follow-up Study of Patients Receiving CAR-T Cells
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants who enrolled in a CAR-T cell therapy clinical trial at Froedtert Hospital and the Medical College of Wisconsin
- Adults aged 18 to 80 years
You will not qualify if you...
- There are no exclusion criteria for this study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Years 2 to 15 post-treatment
Participants who previously received CAR-T cells are followed for persistence of CAR-T cells, development of secondary malignancies, or other medical complications.
Periodic visits over 13 years
Trial Site Locations
Total: 1 location
1
Froedtert Hospital & Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
Research Team
M
Medical College of Wisconsin Clinical Cancer Center
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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