Actively Recruiting
Longitudinal Study on Sexual and Reproductive Health in Women with Breast Cancer and Lymphoma
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-03-04
475
Participants Needed
7
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating how cancer treatments affect sexual and reproductive health in women diagnosed with breast cancer or lymphoma. This observational study aims to understand the prevalence, severity, timing, and factors related to sexual dysfunction in both premenopausal and postmenopausal women. The study also explores how treatments impact fertility and decisions about fertility preservation over a five-year period. Participants will complete detailed surveys on sexual function at several points before starting chemotherapy, then at 3, 6, and 12 months after baseline, and yearly thereafter for up to five years. A subset of premenopausal women on Tamoxifen will also undergo blood draws and transvaginal ultrasounds at specified intervals to assess ovarian function. Blood samples and ultrasounds are optional but help evaluate the biological effects of treatment on fertility. Women will be asked to complete questionnaires related to sexual health and reproductive concerns, with follow-up surveys administered by mail or phone if needed. The study measures the natural history of sexual and reproductive health changes over five years, including predictors of dysfunction and comparisons between breast cancer and lymphoma patients. Participants safety and health data will be monitored throughout, and involvement may last up to five years.
CONDITIONS
Brief Title
Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma
Research Team
S
Shari Goldfarb, MD
J
Jeanne Carter, MD
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