Actively Recruiting
Metabolomic Profile of Vitreoretinal Diseases: an NMR-Based Approach Using Vitreous.
Led by Renmin Hospital of Wuhan University · Updated on 2024-05-28
450
Participants Needed
1
Research Sites
206 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study was to learn about metabolomics profiles in vitreoretinal diseases by nuclear magnetic resonance (NMR)using vitreous fluid. The main question it aimed to answer was abnormal biomarkers for common retinal diseases such as idiopathic macular hole(IMH), diabetic retinopathy(DR) and retinal detachment(RD). Participants would not be subjected to any intervention and the investigators would only collect preoperative information and remaining vitreous samples. The investigators divided the participants into groups with appropriate disease names based on the disease diagnosis, such as IMH group, DR group, and RD group. The MH group was used as a control group, investigators compared other groups to see the metabolomic abnormalities.
CONDITIONS
Official Title
Metabolomic Profile of Vitreoretinal Diseases: an NMR-Based Approach Using Vitreous.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of idiopathic macular hole (IMH) requiring pars plana vitrectomy (PPV) surgery
- Diagnosis of diabetic retinopathy (DR) requiring PPV surgery
- Diagnosis of retinal detachment (RD) requiring PPV surgery
- Diagnosis of idiopathic macular epiretinal membrane (IMM) requiring PPV surgery
- Diagnosis of retinal vein occlusion (RVO) requiring PPV surgery
You will not qualify if you...
- Vitreoretinal disease not requiring PPV surgery
- Previous history of PPV surgery
- Presence of other active eye diseases such as acute conjunctivitis or uveitis
- Presence of serious systemic diseases like hypertension or diabetes mellitus
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Eye, Center, Renmin Hospital of Wuhan University
Wuhan, Hubei, China, 430060
Actively Recruiting
Research Team
L
Liwei Cheng
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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