Actively Recruiting

Phase Not Applicable
All Genders
NCT05553223

Micro-doses of Physical Activity for COPD

Led by University of British Columbia · Updated on 2025-04-04

20

Participants Needed

1

Research Sites

202 weeks

Total Duration

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AI-Summary

What this Trial Is About

Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than healthy individuals. Those who are the most sedentary have a greater risk of heart and blood vessel disease, which may lead to an early death. This project will investigate the effect of sitting still for 3 hours on blood vessel health in individuals with COPD. It will also investigate whether breaking up the amount of time patients sit with regular short bouts of walking (5 minutes each hour) at a comfortable pace chosen by the patient can have a positive effect on maintaining the health of their blood vessels. It is hypothesized that blood vessel health will be worse after 3 hours of sitting compared to when the sitting is broken up by short bouts of walking.

CONDITIONS

Official Title

Micro-doses of Physical Activity for COPD

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-smoking (more than 6 months) patients with stable moderate-to-severe COPD
  • Post bronchodilator forced expired volume in 1 second/forced vital capacity less than 0.7 and below lower limit of normal
  • Forced Expired Volume in 1 second between 30% and 80% predicted
  • Free from COPD exacerbation for more than 6 weeks
Not Eligible

You will not qualify if you...

  • Currently performing structured exercise training or pulmonary rehabilitation
  • History of deep vein thrombosis
  • Taking anticoagulant medication
  • Advanced cardiac or cerebrovascular disease such as heart failure, previous stroke, or myocardial infarction
  • Diabetes
  • Musculoskeletal issues that limit physical activity
  • Unable to obtain vascular ultrasound measurements

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of British Columbia

Kelowna, British Columbia, Canada, V1V2L2

Actively Recruiting

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Research Team

N

Neil Eves, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

2

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