Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT05671419

Mindful Self-Compassion for Anxiety Disorders and Depression

Led by Georgetown University · Updated on 2025-06-13

40

Participants Needed

1

Research Sites

232 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study will compare 8-week Mindful Self-Compassion training, compared to a control group that does not receive the intervention, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety disorder, social anxiety disorder, and panic disorder) or major depressive disorder.

CONDITIONS

Official Title

Mindful Self-Compassion for Anxiety Disorders and Depression

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 75 years
  • Diagnosed with a primary anxiety disorder (social anxiety disorder, generalized anxiety disorder, panic disorder, or agoraphobia) or current major depressive disorder
  • Low self-compassion score as measured by the self-compassion scale
  • Understand study procedures and willing to participate in all testing visits and assigned treatment
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Comorbid psychiatric disorders other than anxiety or depression, including psychotic disorder, obsessive compulsive disorder, eating disorders, bipolar disorder, developmental or organic mental disorders
  • Current substance use disorders or post-traumatic stress disorder within past 6 months
  • Serious medical conditions potentially requiring surgery or hospitalization
  • History of head trauma causing prolonged loss of consciousness or ongoing cognitive impairment
  • Inability to understand study procedures or informed consent, or significant personality dysfunction
  • Non-compliance with study procedures or planned travel during study
  • Taking psychiatric medications such as barbiturates or antipsychotics; stable doses of some antidepressants and sleep medications allowed
  • Psychotherapy started within 1 month prior to screening or ongoing psychotherapy targeting anxiety
  • Completed Mindful Self-Compassion or equivalent meditation training in past year
  • Significant active suicidal ideation or behaviors within past year
  • Medical conditions that may worsen with study treatment (e.g., epilepsy)
  • Adults unable to consent
  • Pregnant women
  • Prisoners

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Georgetown University Medical Center

Washington D.C., District of Columbia, United States, 20007

Actively Recruiting

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Research Team

C

Charisma, Study Coordinator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Mindful Self-Compassion for Anxiety Disorders and Depression | DecenTrialz