Actively Recruiting

Age: 18Years +
All Genders
NCT06880978

Mini-Crush Or Controlled Balloon-Crush For True Coronary Bifurcation Lesions

Led by Istanbul Mehmet Akif Ersoy Educational and Training Hospital · Updated on 2025-03-18

400

Participants Needed

1

Research Sites

73 weeks

Total Duration

On this page

Sponsors

I

Istanbul Mehmet Akif Ersoy Educational and Training Hospital

Lead Sponsor

I

Istanbul Medipol University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The mini-crush technique is one of the leading 2-stent techniques frequently applied by interventional cardiologists to treat complex bifurcation lesions. In the last 20 years, many technical innovations and iterations of mini-crush technique have been developed, and it maintains its popularity among invasive cardiologists. Moreover, mini-crush and double kissing-crush techniques have been compared in terms of clinical results in both left main and non-left main coronary bifurcation patient populations and no significant difference was found. However, the most important challenges of the mini-crush technique are the rewiring and advancement of a 1:1 non-compliant side-branch balloon after the main branch stent has been implanted. These challenges usually necessitate the use of a low profile balloon or additional support maneuvers (such as anchor balloon). Recently, a novel modified mini-crush-crush technique (controlled balloon-crush) has been introduced to the literature and is one of the most up-to-date crush techniques. The main advantage of this technique over the contemporary mini-crush technique is that the side branch can be easily rewired and the 1:1 size non-compliant balloon can easily pass through the crushed stent structure in the ostial part of the side branch. The basic rationale of this is that the crushing of the side branch stent is done in a more controlled manner (by slowly deflation of the side branch stent balloon) and this causes less disruption of the stent cells. This prospective observational study aims to assess the procedural and 1-year clinical outcomes of the contemporary mini-crush and controlled balloon-crush (modified mini-crush) double stenting techniques in patients with true coronary bifurcation lesions.

CONDITIONS

Official Title

Mini-Crush Or Controlled Balloon-Crush For True Coronary Bifurcation Lesions

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged >18
  • Undergoing PCI with mini-crush or controlled balloon-crush stenting
  • Having a complex coronary bifurcation lesion (Medina 0.1.1 or Medina 1.1.1)
Not Eligible

You will not qualify if you...

  • Non-complex bifurcation anatomy
  • Bail-out 2-stent techniques (reverse mini-crush or reverse controlled balloon-crush)
  • ST-elevation myocardial infarction
  • Cardiogenic shock status
  • In-stent restenosis
  • History of coronary artery bypass grafting
  • Implantation of bare-metal stent
  • End-stage hepatic or renal disease
  • Life expectancy less than 1 year

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital

Istanbul, Turkey (Türkiye), 33484

Actively Recruiting

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Research Team

F

Fatih Uzun, Professor

CONTACT

A

Ahmet Güner, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Mini-Crush Or Controlled Balloon-Crush For True Coronary Bifurcation Lesions | DecenTrialz