Actively Recruiting
Morphometric Study of the Muscles of the Skin in MRI 3 Tesla in Patients With Facial Paralysis
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2026-05-13
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating facial paralysis by developing a new, objective way to assess the movement and condition of facial muscles. Currently, facial paralysis is evaluated using subjective scales that do not measure individual muscles. This study aims to link changes in muscle structure seen on MRI scans with facial movements to create clear and repeatable measures for patients with facial paralysis sequelae. Participants include patients with facial paralysis and healthy subjects. The study involves detailed imaging of skin muscles, especially the large zygomatic muscle, using a 3 Tesla MRI scanner. By comparing muscle volume and morphology between patients and healthy individuals, the study hopes to improve the understanding of muscle changes related to facial paralysis and guide surgical decisions. During the study, participants will undergo MRI scans and clinical examinations to capture muscle shape and skin movement. Researchers will measure the volume of the large zygomatic muscle over five years to track differences between patients and healthy people. This non-invasive approach aims to provide objective data to support treatment planning and monitor recovery after facial paralysis or reconstructive surgery.
CONDITIONS
Brief Title
Morphometric Study of the Muscles of the Skin in MRI 3 Tesla in Patients With Facial Paralysis.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with facial paralysis
- Male or female
- 18 years of age or older
You will not qualify if you...
- Pregnancy or breastfeeding
- Contraindication to MRI, including claustrophobia
- Presence of pacemaker, neurosurgical clips, vascular clips, cardiac valves, peritoneal valves, cochlear implant, neuro-stimulator, intra-orbital metal shards, articular prosthesis, dental prosthesis, contact lenses, insulin pumps, intrauterine device, tattoo, piercing, or implants that prevent MRI scanning
- Other conditions preventing safe MRI scanning as listed in criteria
- Any other factors contraindicating MRI use as specified in the trial criteria
- Any metal devices or implants incompatible with MRI scanning as listed in the criteria
- Claustrophobia or conditions making MRI unsafe or impossible to perform
- Lactation or pregnancy status excluding from participation
- Use of medical devices or implants as contraindicated for MRI scanning
- Patients with conditions conflicting with MRI safety as described in exclusion criteria
- Other specified contraindications to MRI scanning as detailed in the eligibility criteria
- Exclusion due to any metal or device presence incompatible with MRI
- Exclusion due to claustrophobia or inability to undergo MRI safely
- Exclusion of pregnant or breastfeeding women
- Exclusion of patients with implants or metal shards that contraindicate MRI scanning
- Any other exclusion criteria related to MRI safety stated in the source text
- Any additional contraindications to MRI scanning detailed in the source criteria
- Exclusion of patients with medical devices that interfere with MRI scanning
- Exclusion of patients with claustrophobia or inability to tolerate MRI scanning
- Exclusion of patients who are pregnant or lactating
- Exclusion of patients with metal implants or devices incompatible with MRI scanning
- Any other MRI-related safety contraindications listed in the protocol
- Exclusion of patients with medical implants or devices incompatible with MRI scanning
- Exclusion of patients with claustrophobia or other MRI contraindications
- Exclusion of patients who are pregnant or breastfeeding
- Exclusion of patients with metal implants or objects contraindicating MRI
- Exclusion of patients with medical devices or implants unsuitable for MRI
- Exclusion of patients with claustrophobia or inability to tolerate MRI
- Any other exclusion criteria related to MRI safety as per the study protocol
- Exclusion of patients with metal or devices incompatible with MRI
- Exclusion of patients with claustrophobia or other contraindications to MRI
- Exclusion of pregnant or breastfeeding patients
- Exclusion of patients with metal or devices that contraindicate MRI
- Exclusion of patients with medical implants or devices incompatible with MRI
- Exclusion of patients with claustrophobia or other MRI contraindications
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or inability to safely undergo MRI
- Exclusion of pregnancy or breastfeeding
- Exclusion of patients with devices or metal incompatible with MRI
- Exclusion of claustrophobia or other MRI safety contraindications
- Exclusion of pregnant or breastfeeding women
- Exclusion of patients with metal implants or devices contraindicating MRI
- Exclusion of claustrophobia or inability to tolerate MRI scanning
- Exclusion of pregnant or breastfeeding women
- Exclusion of patients with metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or other MRI contraindications
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or inability to undergo MRI safely
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or other MRI contraindications
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or inability to safely undergo MRI
- Exclusion of pregnancy or breastfeeding
- Exclusion of patients with metal implants or devices contraindicating MRI
- Exclusion of claustrophobia or inability to tolerate MRI
- Exclusion of pregnant or breastfeeding women
- Exclusion of patients with metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or other MRI contraindications
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or inability to undergo MRI safely
- Exclusion of pregnant or breastfeeding women
- Exclusion of patients with metal implants or devices contraindicating MRI
- Exclusion of claustrophobia or inability to tolerate MRI
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or other MRI contraindications
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or inability to safely undergo MRI
- Exclusion of pregnancy or breastfeeding
- Exclusion of patients with metal implants or devices contraindicating MRI
- Exclusion of claustrophobia or inability to tolerate MRI
- Exclusion of pregnant or breastfeeding women
- Exclusion of patients with metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or other MRI contraindications
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or inability to undergo MRI safely
- Exclusion of pregnant or breastfeeding women
- Exclusion of patients with metal implants or devices contraindicating MRI
- Exclusion of claustrophobia or inability to tolerate MRI
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or other MRI contraindications
- Exclusion of pregnant or breastfeeding patients
- Exclusion of metal implants or devices incompatible with MRI
- Exclusion of claustrophobia or inability to safely undergo MRI
- Exclusion of pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
screening and enrollment visit
Duration - 1 day
Participants undergo a morphometric evaluation of the muscles of the skin using MRI 3 Tesla, focusing on the large zygomatic muscle.
1 visit (in-person)
Duration - 5 years
Participants are observed over time to measure changes in the volume of the large zygomatic muscle compared to healthy subjects.
periodic assessments over 5 years
Trial Site Locations
Total: 1 location
1
CHU Amiens Picardie
Amiens, Picardie, France, 80054
Actively Recruiting
Research Team
S
Stéphanie DAKPE, Dr
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
2
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