Actively Recruiting
Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease
Led by Massachusetts General Hospital · Updated on 2026-03-03
350
Participants Needed
2
Research Sites
233 weeks
Total Duration
On this page
Sponsors
M
Massachusetts General Hospital
Lead Sponsor
U
University of Miami Sylvester Comprehensive Cancer Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to demonstrate the efficacy of a multidisciplinary group-based telehealth intervention (HORIZONS) compared to minimally enhanced usual care for improving self-management and quality of life for hematopoietic stem cell transplant (HSCT) survivors living with chronic graft-versus host disease, and to identify critical facilitators and barriers for HORIZONS implementation and adoption.
CONDITIONS
Official Title
Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (18 years or older) who have undergone allogeneic hematopoietic cell transplant
- Have moderate to severe chronic graft-versus-host disease based on patient report
- Able to participate in English or Spanish language group telehealth intervention
You will not qualify if you...
- Patients with mild chronic graft-versus-host disease based on their self-report
- Patients with a major untreated psychiatric or cognitive condition that interferes with the ability to give informed consent
- Patients with active relapsed disease requiring therapy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
University of Miami Sylvester Comprehensive Cancer Center
Miami, Florida, United States, 33136
Actively Recruiting
2
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
L
Lara Traeger PhD
CONTACT
A
Areej El-Jawahri MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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