Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
ID07588737

Multimodal Artificial Intelligence-Guided Symptom Monitoring and Recovery Management After Lung Cancer Surgery: A 20-Center Prospective Randomized Controlled Trial

Led by The First Affiliated Hospital of Guangzhou Medical University · Updated on 2026-05-15

868

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a multimodal artificial intelligence (AI)-guided postoperative recovery management system for patients after lung cancer surgery. This multicenter, prospective, randomized controlled trial aims to assess the effectiveness and safety of the AI system in improving recovery by monitoring symptoms such as pain, fatigue, disturbed sleep, shortness of breath, and cough. The study compares AI-guided recovery management with usual postoperative care to better support patient recovery and timely intervention. Participants are randomly assigned to either an AI-guided recovery group or a usual care group. The AI-guided group receives standard postoperative care plus an AI system that collects patient symptoms, vital signs, physical activity, respiratory rehab data, and images or videos when needed. The system offers personalized recovery feedback, nursing advice, rehab reminders, activity guidance, and alerts for high-risk conditions. The usual care group receives standard postoperative management and completes symptom assessments but does not get AI-generated feedback. Throughout the 30 days after surgery, participants provide symptom assessments at scheduled times. Researchers monitor symptom threshold events, overall symptom burden, quality of recovery, adherence to rehabilitation and physical activity, healthcare use, pulmonary complications, and readmissions. Safety and feasibility of the AI system are also evaluated. Participants remain connected to usual clinical safety pathways during the study, which lasts from intervention initiation to postoperative day 30.

CONDITIONS

Brief Title

Multimodal AI-Guided Recovery Management After Lung Cancer Surgery

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Clinically or pathologically diagnosed with lung cancer
  • Undergoing lung cancer-related thoracic surgery (video-assisted, robot-assisted, or open thoracic surgery)
  • Surgical extent including wedge resection, segmentectomy, lobectomy, sleeve resection, combined resection, bilobectomy, or pneumonectomy
  • Clinically stable after surgery and able to participate in symptom assessment and recovery management
  • Able to use a smartphone or study device, or has a caregiver who can assist
  • Able to complete patient-reported symptom assessments and recovery information reporting
  • Provides written informed consent
Not Eligible

You will not qualify if you...

  • Receiving non-surgical treatment only
  • Undergoing bronchoscopy, percutaneous biopsy, or other non-surgical diagnostic or therapeutic procedures only
  • Clinically unstable after surgery and unable to participate in symptom assessment or recovery management
  • Requiring prolonged intensive care, continuous advanced life support, or intensive medical management
  • Severe cognitive impairment, psychiatric disorder, language communication disorder, or other conditions preventing study assessments
  • Unable to use a smartphone or study device without caregiver assistance
  • Currently participating in another interventional clinical study that may affect this trial's primary outcome
  • Any other condition judged by the investigator as unsuitable for participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Postoperative Treatment

Duration - From postoperative intervention initiation to postoperative day 30

Participants receive either routine postoperative rehabilitation nursing with conventional internet-based information or artificial intelligence-assisted postoperative rehabilitation nursing. The AI system provides individualized rehabilitation recommendations including pain management, pulmonary function training, and exercise rehabilitation from the start of postoperative intervention to postoperative day 30.

Weekly visits for up to 4 weeks

Postoperative Symptom Assessments

Duration - Postoperative baseline to day 30

Participants complete patient-reported symptom assessments at baseline after surgery and on days 7, 14, and 30 to monitor symptom burden and recovery progress.

4 visits (postoperative baseline, day 7, day 14, day 30)

Trial Site Locations

Total: 1 location

1

the First Affiliated Hospital of Guangzhou Medical University, Guangzhou,Guangdong 510120

Guangzhou, Guangdong, China

Actively Recruiting

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Research Team

J

Jianxing He

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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