Actively Recruiting
Neural Network to Calculate Morphology of the Cleft Palate to Reduce Cleft Lip and Palate Treatment Burden
Led by University Hospital, Basel, Switzerland · Updated on 2025-03-24
450
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University Hospital, Basel, Switzerland
Lead Sponsor
B
Botnar Research Centre for Child Health (BRCCH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are developing a neural network to calculate the three-dimensional shape of the palate in infants with cleft lip and palate deformities. This study aims to reduce the treatment burden for these conditions by using routinely collected data from patients treated at the University Hospital Basel. The neural network will analyze palatal casts and photographs to compute 3D palatal geometry from single images. The study involves collecting data such as palatal casts and intraoral photographs that are routinely taken during patient care. These data include plaster casts, intraoral scans, and corresponding images of the cleft palate from patients treated between 1970 and 2025. This observational study does not involve any interventions or treatments but focuses on data analysis to develop the neural network. Participants provide existing palatal data which researchers will analyze to develop and validate the neural network. The primary outcome measured is the 3D palatal geometry at baseline, computed from the collected images and casts. There are no additional treatments or procedures for participants, and the study involves reviewing existing patient data collected during routine care.
CONDITIONS
Brief Title
Neural Network to Calculate Morphology of the Cleft Palate to Reduce Cleft Lip and Palate Treatment Burden.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with cleft lip and palate malformation with available routinely performed plaster cast model from palatal impressions, intraoral scans from the palate and corresponding images of the cleft palate (1970 till 2025)
You will not qualify if you...
- Existence of a documented rejection
AI-Screening
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Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) or remote screening
Duration - At baseline
Participants provide palatal casts and palatal images taken during routine care for data collection.
1 visit (in-person) for collecting palatal casts and images
Duration - Up to 5 years
Participants’ data are observed over time to analyze 3D palatal geometry and treatment outcomes.
No additional visits; observation based on collected data
Trial Site Locations
Total: 1 location
1
Mund-, Kiefer- und Gesichtschirurgie, Universitätsspital Basel
Basel, Switzerland, 4031
Actively Recruiting
Research Team
B
Benito Benitez, Dr. med. Dr. med. dent.
A
Andreas Müller, PD Dr. med. Dr. med. dent. Dr.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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