Actively Recruiting
Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis
Led by Monash University · Updated on 2025-05-30
1000
Participants Needed
2
Research Sites
330 weeks
Total Duration
On this page
Sponsors
M
Monash University
Lead Sponsor
E
Eastern Health
Collaborating Sponsor
AI-Summary
What this Trial Is About
This cohort study aims to determine if a blood test can aid with diagnosing dementia in anyone presenting with cognitive complaints to a single healthcare network. The investigators will measure levels of a brain protein, Neurofilament light chain (Nfl), and assess changes in language using speech tests. Participants will have a single blood test and speech test, and will be followed up at 12-months to complete questionnaires and cognitive scales over the phone. The speech test will also be completed again at 12-months. Individuals at risk of a Fronto-temporal dementia syndrome will be eligible to complete optional genetic testing involving an 'at home' saliva sample.
CONDITIONS
Official Title
Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- All patients presenting to Eastern Health services with a cognitive complaint or potential neurodegenerative disorder
You will not qualify if you...
- Prognosis less than 12 months
- No cognitive complaint
- Patients not involved within the single healthcare network
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Box Hill Hospital
Box Hill, Victoria, Australia, 3128
Actively Recruiting
2
Wantirna Health
Wantirna, Victoria, Australia, 3152
Actively Recruiting
Research Team
P
Prof. Amy Brodtmann, MBBS, FRACP, PhD, FANZAN
CONTACT
S
Svetlana Ivanic, BSc(Hons)
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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