Significance of resistive index in color Doppler ultrasonogram: differentiation between benign and malignant breast masses.
H Y Choi, H Y Kim, S Y Baek...
https://pubmed.ncbi.nlm.nih.gov/10665344Actively Recruiting
Age: 18Years +
FEMALE
ID07465523
A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation
Led by Ahmet Yesildag · Updated on 2026-03-16
90
Participants Needed
1
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the role of Doppler ultrasound in evaluating breast masses to help distinguish between benign and malignant tumors in female patients. This observational study focuses on analyzing differences in the resistive index (RI) values between the mass and surrounding healthy breast tissue. The study also explores vascular index values using a newer Doppler Microvascular Flow method to improve differentiation based on pathology results. Participants will undergo Doppler ultrasound scans where minimum, maximum, and average RI values from the breast mass and normal tissue will be recorded. The relative differences in these RI values between the mass and healthy tissue will be calculated and compared. Cases will be grouped into benign or malignant categories according to pathology, and threshold values for these measurements will be evaluated. During the study, participants will have their breast masses assessed with Doppler ultrasound. Researchers will collect data on resistive index values and vascular flow patterns. The main outcome measure is the percentage change in resistive index between the mass and surrounding normal tissue over a 3 to 4 month period. This helps determine how well these ultrasound measures distinguish between benign and malignant breast masses, supporting diagnostic accuracy and patient care.
CONDITIONS
Brief Title
A Novel Approach in the Evaluation of Breast Masses With Doppler US
Who Can Participate
Age: 18Years +
FEMALE
Eligibility Criteria
You may qualify if you...
- Female patients
- Age 18 years or older
- Presence of solid breast masses
- Availability of pathology results for the breast mass
You will not qualify if you...
- Presence of hypovascular breast masses
- Presence of cystic breast masses
- Cases with mastitis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Diagnostic Evaluation
Duration - 3 to 4 months
Participants undergo Doppler ultrasound imaging to evaluate breast masses and surrounding tissue using resistive index measurements.
1 to 2 visits for Doppler ultrasound imaging and pathology result collection
Trial Site Locations
Total: 1 location
1
Karamanoğlu Mehmetbey University, KEAH
Karaman, Lütfen Seçiniz., Turkey (Türkiye), 70200
Actively Recruiting
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Research Team
A
Ahmet Yeşildağ, Prof.Dr
G
Gökçe Merve Arman, Dr.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Correlation Between Doppler Ultrasound Blood Flow Parameters and Angiogenesis and Proliferation Activity in Breast Cancer.
Jiacheng Niu, Junxia Ma, Xiangzhen Guan...
https://pubmed.ncbi.nlm.nih.gov/31535669Use of Doppler ultrasound in the evaluation of breast carcinoma.
T S Mehta, S Raza, J K Baum
https://pubmed.ncbi.nlm.nih.gov/11014252