Actively Recruiting

All Genders
NCT05040178

An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

Led by RECORDATI GROUP · Updated on 2025-04-15

20

Participants Needed

5

Research Sites

521 weeks

Total Duration

On this page

Sponsors

R

RECORDATI GROUP

Lead Sponsor

T

Target PharmaSolutions, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

To obtain short-term and long-term clinical safety information, in pediatric and adult patients with PA and MMA treated with Carbaglu®.

CONDITIONS

Official Title

An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed and dated informed consent or assent form provided
  • Prescribed and treated with Carbaglu4
  • Established diagnosis of Propionic Acidemia (PA) or Methylmalonic Acidemia (MMA) confirmed by urine organic acid analysis or molecular genetic testing
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Children's National Hospital

Washington D.C., District of Columbia, United States, 20010

Actively Recruiting

2

University of South Florida

Tampa, Florida, United States, 33606

Actively Recruiting

3

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States, 60611

Actively Recruiting

4

Riley Children's Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

5

Icahn School of Medicine at Mt. Sinai

New York, New York, United States, 10029

Actively Recruiting

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Research Team

A

Anne Marie Cesario

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics | DecenTrialz