Actively Recruiting

Age: 18Years +
All Genders
NCT04282811

Observational Study Relapsed or Refractory Chronic Lymphocytic Leukemia Venetoclax-based Regimens Outside Clinical Trials in Italy

Led by Gruppo Italiano Malattie EMatologiche dell'Adulto · Updated on 2025-01-17

321

Participants Needed

27

Research Sites

275 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Observational study aimed at describing the characteristics and outcome of CLL patients who started treatment with venetoclax-based regimens according to the local label outside clinical trials in Italy in a period of time ranging from the start of the Venetoclax Named Patient Program (March 2016) until June 30th, 2025.

CONDITIONS

Official Title

Observational Study Relapsed or Refractory Chronic Lymphocytic Leukemia Venetoclax-based Regimens Outside Clinical Trials in Italy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with relapsed or refractory Chronic Lymphocytic Leukemia (CLL) who meet the Venetoclax Named Patient Program criteria and have received at least one dose of venetoclax.
  • Patients with CLL who have received at least one dose of venetoclax or are scheduled to start venetoclax before June 30th, 2025.
  • Signed informed consent indicating understanding of the study purpose and agreement to provide full access to medical records, if feasible.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 27 locations

1

Aou Arcispedale Sant'Anna - Cona (Fe) - Uoc Ematologia E Fisiopatologia Della Coagulazione

Cona, Ferrara, Italy

Actively Recruiting

2

Aon Ss. Antonio E Biagio E C. Arrigo - Alessandria - Soc Ematologia

Alessandria, Italy

Actively Recruiting

3

Aou Consorziale Policlinico - Bari - Uo Ematologia Con Trapianto

Bari, Italy

Actively Recruiting

4

Ao Brotzu, Presidio Ospedaliero A. Businco - Cagliari - Sc Ematologia E Ctmo

Cagliari, Italy

Actively Recruiting

5

Ctc U.O Di Ematologia Con Trapianto Di Midollo Osseo - Catania

Catania, Italy

Actively Recruiting

6

Ao Di Catanzaro "Pugliese-Ciaccio", Presidio Ospedaliero "Ciaccio - de Lellis" - Ematologia

Catanzaro, Italy

Actively Recruiting

7

Ao Di Cosenza, Presidio Ospedaliero Annunziata - Uoc Ematologia

Cosenza, Italy

Actively Recruiting

8

Aou Careggi - Firenze - Sod Ematologia

Florence, Italy

Actively Recruiting

9

Ao Ospedali Riuniti "Papardo Piemonte" - Po Papardo - Messina - Sc Ematologia

Messina, Italy

Actively Recruiting

10

Asst Grande Ospedale Metropolitano Niguarda - Milano - Sc Ematologia

Milan, Italy

Actively Recruiting

11

Fondazione Irccs Ca' Granda, Ospedale Maggiore Policlinico - Milano - Ematologia - Padiglione Marcora

Milan, Italy

Actively Recruiting

12

Irccs Ospedale S. Raffaele - Milano - Unità Neoplasie Linfocitarie B

Milan, Italy

Actively Recruiting

13

Aou Di Modena - Sc Ematologia

Modena, Italy

Actively Recruiting

14

Aou Maggiore Della Carita' Di Novara - Scdu Ematologia

Novara, Italy

Actively Recruiting

15

Ao Ospedali Riuniti Villa Sofia Cervello - Palermo - Uo Ematologia Con Utmo

Palermo, Italy

Actively Recruiting

16

Ao Di Perugia, Ospedale S. Maria Della Misericordia - Ematologia E Trapianto Midollo Osseo

Perugia, Italy

Actively Recruiting

17

Aou Pisana - Uo Ematologia Universitaria

Pisa, Italy

Actively Recruiting

18

Ausl Della Romagna, Ospedale "Santa Maria Delle Croci" - Ravenna - Ematologia

Ravenna, Italy

Actively Recruiting

19

Grande Ospedale Metropolitano "Bianchi-Melacrino-Morelli" Po E. Morelli - Reggio Calabria - Uoc Ematologia

Reggio Calabria, Italy

Actively Recruiting

20

Ausl Di Reggio Emilia - Arcispedale Santa Maria Nuova, Irccs - Sc Ematologia

Reggio Emilia, Italy

Actively Recruiting

21

Fondazione Policlinico Universitario Agostino Gemelli Irccs - Roma - Area Ematologica

Roma, Italy

Actively Recruiting

22

Università Degli Studi Di Roma "Sapienza" - Dipartimento Di Medicina Traslazionale E Di Precisione - U.O.C. Ematologia

Roma, Italy

Actively Recruiting

23

Ao S. Maria - Terni - Sc Onco Ematologia

Terni, Italy

Actively Recruiting

24

Aou Città Della Salute E Della Scienza, Ospedale S. Giovanni Battista Molinette - Torino - Sc Ematologia - Università Degli Studi Di Torino

Torino, Italy

Actively Recruiting

25

Aou Città Della Salute E Della Scienza, Ospedale S. Giovanni Battista Molinette - Torino - Sc Ematologia 2

Torino, Italy

Actively Recruiting

26

Asst Dei Sette Laghi, Ospedale Di Circolo E Fondazione Macchi - Uoc Ematologia

Varese, Italy

Actively Recruiting

27

Aou Integrata Di Verona, Policlinico G.B. Rossi - Uoc Ematologia

Verona, Italy

Actively Recruiting

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Research Team

P

Paola Fazi

CONTACT

E

Enrico Crea

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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