MiR-16 regulates crosstalk in NF-κB tolerogenic inflammatory signaling between myeloma cells and bone marrow macrophages.
Jihane Khalife, Jayeeta Ghose, Marianna Martella...
https://pubmed.ncbi.nlm.nih.gov/31593552Actively Recruiting
Led by Ohio State University Comprehensive Cancer Center · Updated on 2026-03-23
5000
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are studying patients with plasma cell diseases, including Multiple Myeloma and AL Amyloidosis, to improve their quality and length of life. They have created a database with patient information, blood samples, and bone marrow tissue to track treatments, their effectiveness, patient well-being, complications, remission duration, and overall survival. The study is observational and aims to support patients through information and clinical team access, as well as to develop better treatments. The study includes tissue banking, where samples are collected at diagnosis, during routine follow-up, or at relapse. This helps create a resource for research to understand these diseases better. The project covers surveillance, contact, and research, offering patients support and education about their condition and clinical trials. Participants will be contacted and followed over time to collect data on their treatments and health status. Researchers will monitor outcomes such as treatment responses and survival, while also providing information and support. The study aims to build a valuable resource for future research to reduce illness and death from these plasma cell disorders, with ongoing observation expected for up to three years.
CONDITIONS
Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 years
Participants are contacted and observed over time for research and surveillance purposes related to plasma cell disorders.
Visits occur during routine follow-up and at times of diagnosis or relapse for tissue collection
Total: 1 location
1
Ohio State University Medical Center
Columbus, Ohio, United States, 43210
Actively Recruiting
T
The Ohio State University Comprehensive Cancer Center
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Jihane Khalife, Jayeeta Ghose, Marianna Martella...
https://pubmed.ncbi.nlm.nih.gov/31593552