Actively Recruiting

Age: 18Years +
All Genders
NCT06821243

Patients with Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention

Led by Regina Elena Cancer Institute · Updated on 2025-02-11

40

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

Sponsors

R

Regina Elena Cancer Institute

Lead Sponsor

U

University of Campania Luigi Vanvitelli

Collaborating Sponsor

AI-Summary

What this Trial Is About

Prospective pilot study, non-interventional, of a biological/radiological nature, which involves the collection of tissue samples, and blood from patients suffering from squamous cell carcinoma of the oropharynx OPSCC for detection of HPV-DNA/RNA and immuno-phenotypic analysis of T cells, study of extracellular vesicles, and dosages of cytokines and chemokines involved in the immune response

CONDITIONS

Official Title

Patients with Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Squamous cell carcinoma of the oropharynx (OPSCC) patients who are candidates for surgery
  • Age greater than 18 years
  • ECOG performance status of 2 or less
  • Signed informed consent to participate and for data processing
Not Eligible

You will not qualify if you...

  • Presence of distant metastases at the time of diagnosis
  • Previous head and neck cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS National Cancer Institute "Regina Elena"

Rome, Rome, Italy, 00144

Actively Recruiting

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Research Team

A

Antonello Vidiri, Medical Doctor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Patients with Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention | DecenTrialz