Actively Recruiting
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Led by Kodiak Sciences Inc · Updated on 2025-09-10
150
Participants Needed
33
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants with Macular Edema Secondary to Inflammation (MESI)
CONDITIONS
Official Title
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults with MESI showing central subfield thickness of 400 microns or more on SD-OCT in the study eye
- Best-corrected visual acuity (BCVA) ETDRS score between 25 and 70 letters (20/40 to 20/320 Snellen equivalent) in the study eye
- Diagnosis of active or inactive non-infectious intraocular inflammation, either acute or chronic, in the study eye
You will not qualify if you...
- Macular edema in the study eye caused by diabetes, retinal vein occlusion, or wet age-related macular degeneration
- Active or suspected ocular or periocular infection in either eye
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 33 locations
1
Research Network Arizona
Scottsdale, Arizona, United States, 85255
Not Yet Recruiting
2
Global Research Management, Inc.
Glendale, California, United States, 91204
Not Yet Recruiting
3
UCLA Stein Eye Institute
Los Angeles, California, United States, 90095
Not Yet Recruiting
4
Stanford Byers Eye Institute
Palo Alto, California, United States, 94303
Not Yet Recruiting
5
California Eye Specialists Medical Group, Inc.
Pasadena, California, United States, 91107
Actively Recruiting
6
California Eye Specialists Medical Group, Inc.
Redlands, California, United States, 92373
Not Yet Recruiting
7
Retina Consultants of Southern California
Redlands, California, United States, 92374
Not Yet Recruiting
8
Retinal Consultants Medical Group Inc
Sacramento, California, United States, 95841
Actively Recruiting
9
Retina Group of New England, PC
Waterford, Connecticut, United States, 06385
Actively Recruiting
10
Retina Group of Florida (Ft. Lauderdale)
Fort Lauderdale, Florida, United States, 33308
Not Yet Recruiting
11
Associated Vitreoretinal and Uveitis Consultants LLC
Carmel, Indiana, United States, 46032
Actively Recruiting
12
Cumberland Valley Retina Consultants
Hagerstown, Maryland, United States, 21740
Actively Recruiting
13
Retina Consultants of Minnesota
Saint Louis Park, Minnesota, United States, 55416
Not Yet Recruiting
14
The Retina Institute
St Louis, Missouri, United States, 63128
Not Yet Recruiting
15
Retina Associates of New York, P.C.
New York, New York, United States, 10075
Not Yet Recruiting
16
North Carolina Retina Associates (Cary)
Cary, North Carolina, United States, 27511
Not Yet Recruiting
17
North Carolina Retina Associates (Wake Forest)
Wake Forest, North Carolina, United States, 27587
Not Yet Recruiting
18
Cascade Medical Research Institute
Springfield, Oregon, United States, 97477
Actively Recruiting
19
Erie Retina Research
Erie, Pennsylvania, United States, 16507
Actively Recruiting
20
Charleston Neuroscience Institute, LLC (Charleston)
Charleston, South Carolina, United States, 29414
Not Yet Recruiting
21
Palmetto Retina Center (West Columbia)
West Columbia, South Carolina, United States, 29169
Actively Recruiting
22
Vanderbilt Eye Institute
Nashville, Tennessee, United States, 37232
Not Yet Recruiting
23
Austin Retina Associates, PLLC (Austin)
Austin, Texas, United States, 78705
Actively Recruiting
24
UT Austin
Austin, Texas, United States, 78712
Not Yet Recruiting
25
Retina Consultants of Texas (Bellaire)
Bellaire, Texas, United States, 77401
Not Yet Recruiting
26
Texas Retina Center
Houston, Texas, United States, 77030
Not Yet Recruiting
27
Retina Consultants of Texas (Katy)
Katy, Texas, United States, 77494
Actively Recruiting
28
Texas Retina Associates (Plano)
Plano, Texas, United States, 75075
Actively Recruiting
29
Austin Retina Associates, PLLC (Round Rock)
Round Rock, Texas, United States, 78681
Not Yet Recruiting
30
Retina Consultants of Texas (San Antonio)
San Antonio, Texas, United States, 78240
Actively Recruiting
31
Retina Consultants of Texas (Woodlands)
The Woodlands, Texas, United States, 77384
Actively Recruiting
32
Pacific Northwest Retina (Bellevue)
Bellevue, Washington, United States, 98004
Not Yet Recruiting
33
Pacific Northwest Retina (Silverdale)
Silverdale, Washington, United States, 98383
Not Yet Recruiting
Research Team
K
Kodiak Sciences Inc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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