Actively Recruiting

Age: 18Years +
All Genders
ID06721169

Minimally Invasive Treatment of Pilonidal Sinus Disease: Which is Better? Phenol or Laser Ablation

Led by Mersin University · Updated on 2026-03-25

64

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Pilonidal sinus disease is a common condition characterized by infection in the skin near the tailbone, often causing pain, itching, and discharge that affect daily life. It mainly affects men aged 20 to 30 and is linked to factors like body hair, thick skin, overweight, and poor hygiene. This research aims to compare two minimally invasive treatments, phenolization and laser ablation, to see which is better for treating pilonidal sinus disease. The study includes two groups: one receiving phenol therapy, which uses a chemical agent to help heal the sinus by destroying the sinus lining, and the other undergoing laser ablation, which uses laser energy to destroy the sinus tracts. Both treatments are minimally invasive alternatives to traditional surgery. Patients with uncomplicated pilonidal sinus disease will receive one of these treatments, with the choice made after discussion with the doctor. Participants will be followed for one year, with assessments on the first day, seventh day, six months, and twelve months after treatment. Researchers will collect data on pain scores, wound complications, hospital stay length, time to return to daily activities, and any recurrence of the disease. Information will be gathered from medical records and patient interviews to compare the outcomes of phenol therapy and laser ablation.

CONDITIONS

Brief Title

Phenol or Laser: Best Minimally Invasive Treatment for Pilonidal Sinus?

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years and older with pilonidal sinus disease
  • Patients who have not had any previous treatment for pilonidal sinus disease
  • Patients with uncomplicated pilonidal sinus
  • Having been diagnosed with pilonidal sinus disease
  • Patients whose descriptive and clinical characteristics are recorded in their medical files
  • Those who have signed the Informed Voluntary Consent Form/Written Consent Form
Not Eligible

You will not qualify if you...

  • Patients who have previously been treated for pilonidal sinus disease
  • Patients with complicated pilonidal sinus disease
  • Patients aged under 18
  • Patients whose descriptive and clinical characteristics are not recorded in their file records
  • Those who have not signed the Informed Voluntary Consent Form/Written Consent Form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit

Treatment

Duration - Single treatment session

Participants receive minimally invasive treatment for pilonidal sinus disease through either phenol therapy or laser ablation as decided with their physician.

1 treatment visit (in-person)

Post-operative Follow-up

Duration - 12 months

Participants are monitored after treatment to assess postoperative complications, recovery, and recurrence of disease.

Follow-up visits on Day 1, Day 7, Month 6, and Month 12 after treatment

Trial Site Locations

Total: 1 location

1

Mersin University

Mersin, Turkey (Türkiye), 33010

Actively Recruiting

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Research Team

H

Hilmi Bozkurt, Assoc Prof

D

Doğuş Parlak, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial

Outcomes of Two Treatments for Uncomplicated Pilonidal Sinus Disease: Karydakis Flap Procedure and Sinus Tract Ablation Procedure Using a 1,470 nm Diode Laser Combined With Pit Excision.

Veysi Hakan Yardimci

https://pubmed.ncbi.nlm.nih.gov/32064640

Short-term outcomes of radical excision vs. phenolisation of the sinus tract in primary sacrococcygeal pilonidal sinus disease: a randomized-controlled trial.

A A Pronk, N Smakman, E J B Furnee

https://pubmed.ncbi.nlm.nih.gov/31278458