Effect of Photofunctionalization With on Titanium Dental Implants A Pilot Study

What this Trial Is About

Researchers are conducting a pilot clinical trial to compare the placement of standard titanium dental implants with implants treated using a surface photofunctionalization technique based on ultraviolet C radiation (UVC). The study aims to evaluate whether this UVC treatment accelerates bone growth on the implant surface and increases the amount of bone bonding, potentially allowing for earlier loading of the implants. This randomized, double-blind, controlled study is carried out at the Complutense University of Madrid in their Master's Degree in Oral Surgery and Implantology program. Participants receive either photofunctionalized implants treated with UVC (experimental group) or standard non-photofunctionalized implants (control group). The study evaluates implant stability quotient (ISQ) at weekly intervals up to four weeks after surgery to assess bone integration and determine if immediate loading of implants can occur before four weeks. Both native bone and grafted bone sites are included. The trial monitors bone regeneration over three months and ISQ and marginal bone loss over twelve months. During the study, patients undergo implant placement surgery with or without bone or soft tissue regeneration. Follow-up assessments include ISQ measurements at 1, 2, 3, and 4 weeks, with bone regeneration evaluated at three months and additional monitoring of marginal bone loss for up to twelve months. The study tracks implant stability and bone healing to provide insights on reducing implant loading times. Total participation lasts at least one year to capture long-term outcomes. Safety and adherence are monitored throughout the study period.

Photofunctionalization With UVC