Actively Recruiting
Potassium-Competitive Acid Blocker Versus Proton Pump Inhibitor as A Part of Bismuth Based Quadruple Therapy for Treatment of Helicobacter Pylori Infection
Led by Tanta University · Updated on 2025-09-12
320
Participants Needed
1
Research Sites
20 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to compare the eradication rate, safety, and patient adherence between potassium-competitive acid blockers (P-CABs) and proton pump inhibitor-based bismuth quadruple therapy in patients with Helicobacter pylori infection.
CONDITIONS
Official Title
Potassium-Competitive Acid Blocker Versus Proton Pump Inhibitor as A Part of Bismuth Based Quadruple Therapy for Treatment of Helicobacter Pylori Infection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Both sexes are eligible
- Confirmed Helicobacter pylori infection by stool antigen (3rd-gen ELISA) or urea breath test
- No previous treatment for Helicobacter pylori eradication
You will not qualify if you...
- Previous Helicobacter pylori eradication treatment
- Use of antibiotics, proton pump inhibitors, or bismuth within 4 weeks before the study
- History of gastric surgery
- Presence of major organ failure
- Pregnancy or breastfeeding
- Known allergies to any study medications
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tanta University
Tanta, El-Gharbia, Egypt, 31527
Actively Recruiting
Research Team
M
Mohamed G Flefel, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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