Actively Recruiting

Age: 18Years - 85Years
All Genders
NCT04899635

POWER Myocardial Fatigue Study: a Biomechanical Assessment of Contractility of Human Myocardium

Led by University Hospitals Coventry and Warwickshire NHS Trust · Updated on 2024-06-18

100

Participants Needed

1

Research Sites

195 weeks

Total Duration

On this page

Sponsors

U

University Hospitals Coventry and Warwickshire NHS Trust

Lead Sponsor

C

Coventry University

Collaborating Sponsor

AI-Summary

What this Trial Is About

To gain a comprehensive understanding of the biomechanical behaviour of human heart to explore the concept of myocardial fatigue in response to a temporal range of preload, afterload and drug-induced inotropy using in-vitro contractile assays.

CONDITIONS

Official Title

POWER Myocardial Fatigue Study: a Biomechanical Assessment of Contractility of Human Myocardium

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 85 years undergoing open-heart surgery who can provide consent
  • Healthy donor hearts deemed non-transplantable with consent from a legal representative
Not Eligible

You will not qualify if you...

  • Patients lacking the mental capacity to provide consent
  • Patients with ongoing blood-borne infections such as HIV
  • Patients with a recent positive COVID-19 test within 10 days prior to screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospitals Coventry and Warwickshire

Coventry, United Kingdom, CV22DX

Actively Recruiting

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Research Team

P

Patrick Tran

CONTACT

P

Patrick Tran

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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