Actively Recruiting
Pre-myeloid Cancer and Bone Marrow Failure Clinic Study
Led by Mayo Clinic · Updated on 2026-02-23
2000
Participants Needed
3
Research Sites
973 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial tests next generation sequencing (NGS) for the detection of precursor features of pre-myeloid cancers and bone marrow failure syndromes. NGS is a procedure that looks at relevant cancer associated genes and what they do. Finding genetic markers for pre-malignant conditions may help identify patients who are at risk of pre-myeloid cancers and bone marrow failure syndromes and lead to earlier intervention.
CONDITIONS
Official Title
Pre-myeloid Cancer and Bone Marrow Failure Clinic Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with idiopathic cytopenias of unclear significance (ICUS)
- Patients with clonal hematopoiesis of indeterminate significance (CHIP), including VEXAS syndrome
- Patients with clonal cytopenias of undetermined significance (CCUS)
- Patients with marrow failure syndromes linked to myeloid malignancy risk such as telomere dysfunction or chromosomal breakage disorders
- Patients with germline inherited syndromes at risk for malignancy (e.g., GATA2, CEBPA, ETV-6, RUNX1, JAK2, PF6)
- Patients with low risk myelodysplastic syndrome (idiopathic dysplasia of unclear significance)
- Family members of patients with any of the above conditions
- Patients at high risk or suspected of developing any of the above conditions
You will not qualify if you...
- Patients under 18 years of age
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
Actively Recruiting
2
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224-9980
Actively Recruiting
3
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
D
Dani Rud
CONTACT
C
Clinical Trials Referral Office
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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