Actively Recruiting
Study on the Prediction Model of Recurrence and Carcinogenesis Risk of Colorectal Adenoma Based on the Fusion of Traditional Chinese and Western Medicine Multimodal Features
Led by Beijing Friendship Hospital · Updated on 2026-05-28
3000
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are developing a risk prediction model to estimate the chances of colorectal adenoma coming back or turning into cancer by combining features from Traditional Chinese Medicine (TCM) and Western medicine. This project, led by Dr. Wei Hongtao at Beijing Friendship Hospital, uses clinical data from both medical systems to build a model that can help identify patients at higher risk. The study involves recruiting patients with colorectal adenomas from multiple centers across the country and follows strict diagnostic standards from both TCM and Western medicine. Participants in this observational study are patients diagnosed with colorectal adenoma who have undergone endoscopic removal procedures like endoscopic mucosal resection, endoscopic submucosal dissection, or cold snare polypectomy, with pathology confirming the adenoma. Data collected include demographic information, TCM clinical features such as syndromes and tongue and pulse diagnosis, and Western clinical features including endoscopic data. Various algorithms analyze these multimodal data to build and evaluate the risk prediction model, aiming also to find key patient groups for better TCM treatment strategies. During the study, participants will be regularly observed and followed up for up to three years, with an average follow-up time of 1.5 years. Assessments include colonoscopies and laboratory tests to track recurrence of adenomas and advanced adenomas. The study collects comprehensive clinical data and monitors participants carefully to ensure data accuracy. Outcomes focus on the rate of advanced adenoma recurrence and overall adenoma recurrence during the study period. The project also includes training graduate students and publishing scientific papers based on the findings.
CONDITIONS
Brief Title
Prediction Model of Colorectal Adenoma Recurrence-Carcinogenesis Risk With TCM-WM Multimodal Feature Fusion
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meet the diagnostic criteria for colorectal adenoma (Western medicine) and the relevant TCM syndromes.
- Aged 18 years or older.
- Willing to undergo regular follow-up examinations (including colonoscopy and laboratory tests) and sign the informed consent form.
You will not qualify if you...
- Pregnant or lactating women.
- History of Crohn's disease, ulcerative colitis, or other malignancies.
- Previous history of radiotherapy, chemotherapy, or gastrointestinal surgery.
- Hereditary polyposis syndromes (e.g., familial adenomatous polyposis, MUTYH-associated polyposis, or hamartomatous polyposis syndrome).
- Severe cognitive impairment, dementia, or mental illness.
- Severe cardiovascular or cerebrovascular diseases, or hematological system disorders.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 3 years (average 1.5 years)
Participants who have undergone endoscopic resection for colorectal adenoma are observed with regular follow-up examinations including colonoscopy and laboratory tests to monitor for adenoma recurrence and carcinogenesis risk based on traditional Chinese and Western medicine features.
Regular follow-up examinations including colonoscopy and laboratory tests
Trial Site Locations
Total: 1 location
1
Beijing Friendship Hospital Affiliated to Capital Medical University
Beijing, Beijing Municipality, China, 100000
Actively Recruiting
Research Team
H
Hongtao Wei
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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