Actively Recruiting

Age: 18Years - 72Years
All Genders
Healthy Volunteers
ID05756582

Cross-sectional Study on Prevalence of Latent Tuberculosis Infection in Health-care Workers and Students. A GENERATOR Infrastructure.

Led by Eleonora Nucera · Updated on 2024-02-13

2040

Participants Needed

1

Research Sites

24 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to understand how common Latent Tuberculosis Infection (LTBI) is among health care workers and students. LTBI means being infected with Mycobacterium tuberculosis without showing symptoms of active disease. The study also explores possible risk factors for LTBI in a large group of health care workers and students associated with a major hospital and medical school in Rome. Participants include health care workers from a large tertiary hospital and students from various medical-related degree programs trained at the same hospital. They will complete a brief 9-item multiple-choice questionnaire on a tablet, which explains the study's goals and gathers relevant data. The study is cross-sectional, meaning it captures information at one point in time. During the study, participants will provide information through the questionnaire, which covers demographics, vaccination history, work exposure, and health background. The key measurement is the prevalence of LTBI, determined using specific tests including the QuantiFERON-TB Gold test and medical evaluation to exclude active tuberculosis. The study collects data on various factors like age, sex, smoking, and medical history, all at enrollment. Participation involves a one-time survey, and the study ends after this data collection.

CONDITIONS

Brief Title

Prevalence of Latent Tuberculosis Infection in Health-care Workers and Students

Who Can Participate

Age: 18Years - 72Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • All health-care workers at Fondazione Policlinico Universitario A. Gemelli IRCCS in Rome
  • All students in three-year, single-cycle, master's, or graduate medical degree courses trained at the Fondazione Policlinico Universitario A. Gemelli IRCCS
  • Written informed consent to participate
Not Eligible

You will not qualify if you...

  • Denied informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants complete a questionnaire and undergo diagnostic tests to determine the presence of latent tuberculosis infection.

1 visit (in-person)

Surveillance

Duration - Cross-sectional assessment at enrollment

Participants are observed to assess the prevalence of latent tuberculosis infection and potential risk factors through survey data.

No additional visits required

Trial Site Locations

Total: 1 location

1

UOSD Allergologia e Immunologia Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS

Roma, Italy, 00168

Actively Recruiting

Loading map...

Research Team

A

Angela Rizzi, MD, PhD

R

Raffaella Chini, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Similar Trials

Biodistribution and Pathophysiology Study of 18F-Fibroblast ...

Tuberculosis, Pulmonary

Actively Recruiting

1 location

A Multicenter, Open-label, Randomized, Active-controlled Cli...

Tuberculosis

Actively Recruiting

7 locations

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

An interoperable web-based platform to support health surveillance against latent tuberculosis infection in health care workers and students: The evolution of CROSSWORD study protocol.

Angela Rizzi, Eleonora Nucera, Walter Mazzucco...

https://pubmed.ncbi.nlm.nih.gov/40132007