Study of Hyperkalemia Frequency and Risk Factors in Adults with Chronic Kidney Disease Not on Dialysis Conducted in Community Primary Care Settings

What this Trial Is About

Researchers are investigating how common hyperkalemia is and what risk factors contribute to it among patients with chronic kidney disease CKD who are not on dialysis. This observational study focuses on people receiving primary care in the community and aims to improve understanding by collecting detailed clinical and lifestyle information. The study is being conducted across 18 community health centers and hopes to create a risk prediction model to guide better screening and management of hyperkalemia in CKD patients. The study includes two phases an initial validation phase with 500 participants to check the accuracy of point-of-care testing POCT devices measuring blood potassium, glucose, creatinine, uric acid, and hemoglobin, followed by a main phase with 1,500 participants to assess hyperkalemia prevalence and related risk factors. Blood samples are collected for both POCT and laboratory testing, and participants complete structured questionnaires about their demographics, health conditions, and lifestyle habits. No treatments or interventions are given, as this is an observational study. Participants provide blood samples and answer interviews or questionnaires during their enrollment visit. Researchers measure potassium levels and other blood markers using both POCT and laboratory methods. They also collect data on age, CKD stage, and other health factors to analyze their connection to hyperkalemia. The main outcome is the prevalence of hyperkalemia at enrollment. The study findings will help develop a predictive model to improve early detection and management of hyperkalemia in community-based CKD care.

Prevalence and Risk Factors of Hyperkalemia in Non-Dialysis Chronic Kidney Disease Patients in Community