Assessing the Impact of Transition and Peripheral Zone PSA Densities Over Whole-Gland PSA Density for Prostate Cancer Detection on Multiparametric MRI.
Omer Tarik Esengur, Emma Stevenson, Hunter Stecko...
https://pubmed.ncbi.nlm.nih.gov/39996409/Actively Recruiting
Led by National Cancer Institute (NCI) · Updated on 2026-06-25
10000
Participants Needed
1
Research Sites
156 weeks
Total Duration
This research aims to improve understanding of prostate cancer by collecting data about its radiological and clinical progression. Researchers are studying imaging-based markers that might help profile prostate cancer, which could lead to better diagnosis and treatment decisions. The study focuses on men aged 18 and older who are diagnosed with or suspected of having prostate cancer. Participants include men at increased risk for prostate cancer or those with prostate cancer or suspicious lesions. The study involves gathering imaging and clinical data over at least five years, including multiparametric MRI scans and medical history from visits to the National Cancer Institute or external providers. This data is analyzed to identify imaging markers related to prostate cancer. During the study, participants medical records and imaging results will be reviewed and collected for analysis. Researchers measure associations between imaging features and clinical or pathological factors over a 10-year period. The study does not involve experimental treatments, and participant involvement consists mainly of data collection and monitoring over time.
CONDITIONS
Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer
Y
Yolanda L McKinney, R.N.
I
Ismail B Turkbey, M.D.
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National Cancer Institute (NCI)
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit
Duration - At least 5 years
Participants' imaging and clinical data are collected and reviewed over several years to study prostate cancer progression and outcomes.
Periodic clinical visits and imaging scans
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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https://pubmed.ncbi.nlm.nih.gov/38713024/National Cancer Institute (NCI)
Lead Sponsor