Actively Recruiting
Prospective Evaluation of Topical Almond Oil vs Hydroquinone
Led by University of California, Davis · Updated on 2025-09-12
50
Participants Needed
1
Research Sites
265 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to analyze facial pigmentation and skin microbiome changes after topical almond oil application, compared to the use of topical hydroquinone.
CONDITIONS
Official Title
Prospective Evaluation of Topical Almond Oil vs Hydroquinone
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Premenopausal women of Fitzpatrick skin types 3 to 6
You will not qualify if you...
- Allergy to nuts
- Current smokers, those who have smoked within the past year, or former smokers with more than a 20 pack year history
- Autoimmune photosensitive conditions or genetic collagen disorders such as Ehlers-Danlos syndrome
- Hormonal medications or therapies unless stable for at least 2 months
- Cosmetic facial procedures within 4 months prior to enrollment or deeper chemical peels within 1 year
- Unwillingness to stop vitamin E supplements and foods during the study
- Unwillingness to stop topical cosmetic products during the study
- Unwillingness to complete a two-week washout of topical treatments affecting facial pigmentation, including retinoids, antioxidants, pigment-reducing agents (except study hydroquinone), or nut oils/extracts
- Use of other topical products prohibited one week before each visit except study products
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UC Davis Department of Dermatology, Clinical Trials Unit
Sacramento, California, United States, 95816
Actively Recruiting
Research Team
I
Iryna Rybak
CONTACT
A
Alexis Carrington
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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